ImagePro chroma analysis, n=34; p<0.001.
Brighter-looking skin, measured over eight weeks.
Standardized photography and ImagePro analysis documented a progressive facial-brightness story, with favorable Week 8 results across brightness, hyperpigmentation, and the appearance of dark marks following acne.
ImagePro analysis, n=34.
Targeted subgroup, n=13; p=0.016.
A complexion that looked progressively brighter with continued use.
Measurement-first evidence
A trained technician captured standardized facial images at Baseline and Weeks 2, 4, and 8. ImagePro software provided instrument-based measurement of four appearance endpoints.
Mean improvement describes the average measured change. “Participants improved” describes how many individuals moved in the favorable direction. Both are shown without blending them.
Independent photographic evidence, presented with its full endpoint context.
Complete ImagePro time course
| Endpoint | Timepoint | Mean ± SD | Mean change | Improved | p-value |
|---|---|---|---|---|---|
| Hyperpigmentation (n=21) | Baseline | 91.7 ± 31.7 | - | - | - |
| Hyperpigmentation | Week 2 | 91.3 ± 31.4 | -0.4% | 43% | 0.627 |
| Hyperpigmentation | Week 4 | 94.1 ± 32.2 | +2.6% | 76% | 0.005 |
| Hyperpigmentation | Week 8 | 94.0 ± 31.5 | +2.5% | 76% | 0.021 |
| Dark acne-scar appearance (n=13) | Baseline | 182.7 ± 9.1 | - | - | - |
| Dark acne-scar appearance | Week 2 | 183.3 ± 9.3 | +0.3% | 62% | 0.346 |
| Dark acne-scar appearance | Week 4 | 182.1 ± 9.6 | -0.3% | 38% | 0.428 |
| Dark acne-scar appearance | Week 8 | 184.9 ± 10.2 | +1.2% | 77% | 0.016 |
| Facial brightness (n=34) | Baseline | 26.2 ± 6.9 | - | - | - |
| Facial brightness | Week 2 | 26.2 ± 6.8 | 0.0% | 50% | 0.780 |
| Facial brightness | Week 4 | 26.8 ± 7.1 | +2.3% | 76% | 0.001 |
| Facial brightness | Week 8 | 27.5 ± 6.8 | +5.0% | 88% | <0.001 |
| L* lightening endpoint (n=34) | Baseline | 77.2 ± 6.0 | - | - | - |
| L* lightening endpoint | Week 2 | 77.2 ± 6.1 | 0.0% | 47% | 0.973 |
| L* lightening endpoint | Week 4 | 77.0 ± 6.0 | -0.3% | 35% | 0.130 |
| L* lightening endpoint | Week 8 | 77.4 ± 5.8 | +0.3% | 85% | 0.041 |
Increase was defined as improvement by the source. Hyperpigmentation used Subjects 1-21; dark acne-scar appearance used Subjects 22-34; brightness and L* used all 34 participants.
Results apply to C-Bright Dark Spot Correcting Serum SGF22003-00 / IK101521A under the reported eight-week study design.
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