SenePlex+® Normal-to-Dry Three-Product Regimen

Immediate hydration. Visible refinement at eight weeks.

Independent testing of the Normal-to-Dry regimen documented fast hydration, visible radiance and firmness benefits over eight weeks, plus improved exfoliation in a separate controlled Evening Moisturizer study.

3-product regimen8 weeks32 participants completedInstrument + expert gradingControlled exfoliation study

49.99%

immediate increase in hydration

After first use

Corneometer, n=32; p<0.001.

28.62%

increase in hydration

Week 8

Corneometer, n=31; p<0.001.

23.60%

improvement in visible radiance

Week 8

Expert grading, n=32; p<0.001.

Study A · three-product regimen

Hydration was immediate - and remained significantly improved at Week 8.

Immediate hydration49.99%

n=32; p<0.001.

Week 8 hydration28.62%

n=31; p<0.001.

Week 8 expert-graded radiance23.60%

n=32; p<0.001; 96.88% improved.

Week 8 R0 firmness6.59%

n=32; p=0.033.

100%said skin felt more moisturized.

100%said skin texture felt smoother.

100%said skin tone looked redefined and more supple.

96.88%said skin appeared more luminous, radiant, and bright.

Regimen-level evidence

Study A tested the cleanser, DayTime Moisturizer, and Evening Moisturizer together. Results apply to the tested three-product regimen.

SenePlex+® Beauty Book visual story

A closer look at the skin visuals featured in the 2024 SeneGence Beauty Book.

Week 0

Week 2

Week 4

Before image from the 2024 SeneGence Beauty Book — Before

After image from the 2024 SeneGence Beauty Book — After

2024 SeneGence Beauty Book brand imagery

Week 0, Week 2 and Week 4 skin visuals are presented alongside the Beauty Book’s featured before-and-after eye-area imagery. Measured study outcomes are reported in Studies A and B.

Study B · Essex Evening Moisturizer study

Faster visible surface-stain clearance supported improved exfoliation.

Essex compared Evening Moisturizer SGF21090-01-treated and untreated sites on the same participants. Mean stain extinction occurred at 15.5 ± 0.4 SE days on treated sites versus 18.0 ± 0.4 SE days on untreated sites - 2.5 days sooner (n=33; p<0.001).

Essex Panel 22107; n=33 completers. Evening Moisturizer SGF21090-01-treated and untreated sites were compared within each participant. Differences were significant on Days 2-18 (p≤0.003; p<0.001 except Day 4).

2.5 days

earlier mean stain extinction

Treated vs untreated

15.5 vs 18.0 days; n=33; p<0.001.

0.00 vs 0.18

residual surface-stain intensity

Day 18 · treated vs untreated

Raw Essex milestone; lower indicates less residual stain.

33

participants completed

20-day study

Within-participant treated-site comparison.

Surface-renewal result

This validated surface-stain method measured exfoliation performance of Evening Moisturizer SGF21090-01 as a complete finished formula, supporting improved exfoliation through faster visible clearance.

Technical study record

Two independent studies with precise product attribution.

Study A laboratoryValidated Claim Support, LLC

Study A reportCS211017 / RE211017.V01

Study A products3 in 1 Cleanser SGF21095-00; DayTime Moisturizer SGF2111-00; Evening Moisturizer SGF21090-01

Study A design8-week single-arm regimen study; 34 enrolled / 32 completed

Study B laboratoryEssex Testing Clinic

Study B panel22107

Study B productEvening Moisturizer SGF21090-01

Study B design20-day treated-site vs untreated-site comparison; 33 completed

Selected substantiated outcomes

Selected substantiated outcome	Immediate	Week 2	Week 4	Week 8
Corneometer hydration	+49.99%; p<0.001	+12.54%; p=0.005	+11.98%; p=0.003	+28.62%; p<0.001
Cutometer R0 firmness	-	+7.06%; p=0.016	-	+6.59%; p=0.033
Expert-graded radiance	-	-	-	+23.60%; p<0.001

Hydration increase, firmer R0 readings and expert-graded radiance provide the central regimen results.

Participant experience

Week 8 participant perception	Agreement
Skin feels more moisturized	100%
Skin texture feels smoother	100%
Skin tone looks redefined and more supple	100%
Skin appears more luminous, radiant and bright	96.88%

Self-reported agreement, n=32.

Independent laboratory evidence

Original source pages follow.

View the complete source record.

The complete two-page Essex topline follows, preserving the laboratory identity, tested formula, study design, full time course and aggregate findings. The VCS regimen study identifiers and aggregate results are presented in the technical section above.

The complete PDF pairs this consumer summary with the selected independent laboratory source pages.

Open full PDF + laboratory source

LaboratoryEssex Testing Clinic

Panel22107

Tested formulaEvening Moisturizer SGF21090-01

Study design20-day treated-site comparison

Source authentication

The reproduced Essex Panel 22107 pages retain the original laboratory letterhead and reported study details.

Source note

One participant code was replaced with “One participant” to protect privacy; aggregate study findings are unchanged.

The complete PDF includes the Essex Panel 22107 laboratory pages. One participant code was removed; aggregate findings are unchanged.