ImagePro chroma analysis, n=34; p<0.001.
SeneGenceReviewC-Bright Dark Spot Corrector: brighter-looking skin, measured over eight weeks.
By SeneGence · Updated
Standardized photography and ImagePro analysis documented progressive changes in facial brightness, with favorable Week 8 results for brightness, hyperpigmentation, and the appearance of dark marks following acne.

ImagePro analysis, n=34.
Targeted subgroup, n=13; p=0.016.
Study design and limits
How this study was built, and what that means for reading its numbers.
- The eight-week study was single-arm: 34 women used C-Bright, and each result is compared with that woman’s own baseline images rather than with an untreated group.
- Each endpoint used its own panel. Brightness used all 34 participants, hyperpigmentation 21, and dark marks following acne 13.
- Week 2 changes were not statistically significant on any endpoint; the complete time-course table shows every p-value.
- The Essex Testing Clinic topline summary notes that it has undergone preliminary review by Quality Assurance.
C-Bright Dark Spot Corrector clinical results
SeneGenceReviewA complexion that looked progressively brighter with continued use.
Measurement-first evidence
A trained technician captured standardized facial images at Baseline and Weeks 2, 4, and 8. ImagePro software provided instrument-based measurement of four appearance endpoints.
Mean improvement describes the average measured change. “Participants improved” describes how many individuals moved in the favorable direction. Both are shown without blending them.
SeneGenceReviewIndependent photographic evidence, presented with its full endpoint context.
Complete ImagePro time course
| Endpoint | Timepoint | Mean ± SD | Mean change | Improved | p-value |
|---|---|---|---|---|---|
| Hyperpigmentation (n=21) | Baseline | 91.7 ± 31.7 | - | - | - |
| Hyperpigmentation | Week 2 | 91.3 ± 31.4 | -0.4% | 43% | 0.627 |
| Hyperpigmentation | Week 4 | 94.1 ± 32.2 | +2.6% | 76% | 0.005 |
| Hyperpigmentation | Week 8 | 94.0 ± 31.5 | +2.5% | 76% | 0.021 |
| Dark acne-scar appearance (n=13) | Baseline | 182.7 ± 9.1 | - | - | - |
| Dark acne-scar appearance | Week 2 | 183.3 ± 9.3 | +0.3% | 62% | 0.346 |
| Dark acne-scar appearance | Week 4 | 182.1 ± 9.6 | -0.3% | 38% | 0.428 |
| Dark acne-scar appearance | Week 8 | 184.9 ± 10.2 | +1.2% | 77% | 0.016 |
| Facial brightness (n=34) | Baseline | 26.2 ± 6.9 | - | - | - |
| Facial brightness | Week 2 | 26.2 ± 6.8 | 0.0% | 50% | 0.780 |
| Facial brightness | Week 4 | 26.8 ± 7.1 | +2.3% | 76% | 0.001 |
| Facial brightness | Week 8 | 27.5 ± 6.8 | +5.0% | 88% | <0.001 |
| L* lightening endpoint (n=34) | Baseline | 77.2 ± 6.0 | - | - | - |
| L* lightening endpoint | Week 2 | 77.2 ± 6.1 | 0.0% | 47% | 0.973 |
| L* lightening endpoint | Week 4 | 77.0 ± 6.0 | -0.3% | 35% | 0.130 |
| L* lightening endpoint | Week 8 | 77.4 ± 5.8 | +0.3% | 85% | 0.041 |
Increase was defined as improvement by the source. Hyperpigmentation used Subjects 1-21; dark acne-scar appearance used Subjects 22-34; brightness and L* used all 34 participants.
Results apply to C-Bright Dark Spot Correcting Serum under the reported eight-week study design.
Original source pages follow.
View the complete source record.
The complete two-page Essex laboratory summary follows.
The complete PDF pairs this consumer summary with the selected independent laboratory source pages.
Open complete laboratory report (PDF)Independent laboratory source pages are included in the complete PDF. Participant-identifying information has been removed where indicated; aggregate findings are unchanged.
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