The SeneGence legend
SeneGence is the high-performance skincare and cosmetics company Joni Rogers-Kante founded in 1999 with LipSense® Long-Lasting Liquid Lip Color, our transfer-proof long-lasting liquid lipstick. She carried one question to Vanuatu: How does life flourish in conditions designed to destroy it?
Why SeneGence
Long-wear color, anti-aging skincare and easy routines work together as one day-and-night system you can make your own.
Choose LipSense® Long-Lasting Liquid Lip Color for up to 18 hours of wear with three thin layers and compatible Moisturizing Gloss. Prefer one-step color? LipSense® Cream brings bold, full-coverage color with up to six hours of waterproof, smudge-resistant and transfer-resistant wear from one non-drying layer, in matte, satin and shine finishes, based on our internal panelist study.
For LipSense® Long-Lasting Liquid Lip Color, preparation, lip condition, food, oils and application help shape your wear.
Beauty Book 2026 (p.39).
Where skincare meets Long-Lasting Cosmetics
SeneGence carries SenePlex+® from skincare into its foundations and shadows. You wear it in MakeSense® Original Foundation, BlushSense® Cream Blush and ShadowSense® Eyeshadow, so the color you wear through the day continues your anti-aging routine. ShadowSense blends as a crème and sets to a soft powder for waterproof, fade-resistant eye color.
MakeSense® Original Foundation is made with 90% skincare ingredients. BlushSense® Cream Blush is made with 90% skincare ingredients. ShadowSense® Eyeshadow is made with 75% skincare ingredients. Beauty Book 2026 (pp.27–28, 30).
Start with the result that matters to you: hydration, the look of facial volume or visible surface renewal. See the product, the measurement and the study behind each one.
a mean 73.9%
In an independent eight-week study of 31 women ages 38–75, SeneCell™ SenePlex+® StemCell Concentrate improved measured skin hydration by a mean 73.9% immediately after application, assessed by a skin-moisture meter compared with baseline.
81% of subjects improved
At eight weeks, 81% of participants showed image-analyzed improvement in the look of facial volume after using GLP Complex™ with SenePlex+® and Exosomes.
up to 100% greater
In an independent 20-day study, Evening Moisturizer – Normal to Dry with SenePlex+® showed up to 100% greater visible surface-cell turnover than untreated skin by day 18.
Start with clean skin, then pump Climate Control onto the back of your hand and palette it over face and neck for hydration. Choose targeted care for your skin, follow with moisturizer, then create your color.
Use the remover made for your long-wear formula and settle into evening care.
Add the steps that serve you.
Explore orchid stem cells in SeneCell and the lipid care of Nangai Oil, inspired by skin’s own lipids, as you discover ingredients for softer, more resilient-looking skin. Meet peptides, microbiome skincare and the exosome story behind GLP Complex, with each formula’s own results close by.
Nangai Oil is a biomimetic* facial oil.
We formulate to the European Union cosmetic standard, which prohibits 1,700+ substances.
The Naked Bottle Philosophy leaves out the individual retail outer carton, keeps ingredients and directions on the container, and puts the money that would have gone into cardboard into the formula.
The SeneGence Green Initiative has a wider goal of reducing our carbon footprint.
Joni Rogers-Kante founded SeneGence with LipSense in 1999, inspired by a wish for lip color that would stay with her day. The name joins senescence and intelligence: aging intelligently. In the summer of 2000 she traveled to Vanuatu; follow that story into the orchid research, Nangai Oil and volcanic ash that helped shape the catalogue.
More of the story:
Because beauty should do more than last.
Our anti-aging and longevity beauty brings morning skincare, long-wear color infused with care and evening skincare into one 24-hour system. MakeSense® Original Foundation and BlushSense® Cream Blush each carry SenePlex+® for anti-aging care and are each made with 90% skincare ingredients. Anti-aging and longevity beauty
Calanthe discolor orchid stem cells, yeast-and-kelp bioferments and true extremophile ingredients bring nature into our anti-aging technology. We formulate to the European Union cosmetic standard, which prohibits 1,700+ substances. Our formulas are paraben-free. Our Clean Beauty standard
Long-wear color can continue your skincare through the day. We took the long-wear technology behind LipSense® into our color cosmetics and infused the formulas with skincare actives, so the makeup you wear through the day continues your anti-aging care. The day-to-night beauty system
Morning skincare, color infused with care through the day, deliberate removal and evening skincare belong to one 24-hour beauty system, with less reapplication and more comfort as you go. The day-to-night beauty system
OUR 2026 SUSTAINABILITY REPORT
1.2 million+ outer cartons avoided since 2002
75% less single-use plastic purchased in 2026
14% less non-renewable energy used in 2026
Start with what you want to see
Community questions
Explore our guides and answers to these community questions. Alan Rogers Kante co-owns SeneGence; the discussions are brand-affiliated.
