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clinical finding

Ornithine + Phospholipids + Glycolipids — 30- and 60-day wrinkle-depth, roughness, and smoothness study

product or technology studied

Ingredient study of Ornithine, Phospholipids, and Glycolipids

the finding

At day 30, Primos 3D profilometry measured 9.5% lower nasolabial-fold depth and 5.9% lower skin roughness on the side using the 2% ingredient combination; dermatologist scoring found 31.6% smoother-looking skin at day 30 and 42.1% at day 60; end-of-study positive opinions ranged from 70% for a smoother-looking lip contour to 90% for smoother, firmer, and less tired-looking skin.

The Ornithine, Phospholipids, and Glycolipids combination paired 3D-measured fold-depth and roughness changes with dermatologist-rated smoothness at 30 and 60 days and positive end-of-study feedback on smoothness, firmness, rested appearance, plumpness, lift, and lip contour.

For a customer: The measured and dermatologist-rated findings help explain why Ornithine HCl, Phospholipids, and Glycolipids are used in GLP Complex™ to support smoother-, fuller-looking contours.

updated 2026-08-03 · clinical finding

Complete measurements and study notes10 details
How it was evaluated
Randomized split-face comparison; 2% ingredient-combination cream versus placebo, applied twice daily; Primos 3D profilometry at day 30, dermatologist clinical smoothness scoring at days 30 and 60, and an end-of-study self-assessment questionnaire
Who took part
20 healthy women ages 40–60 with wrinkles, especially nasolabial folds; the questionnaire respondent count is not separately reported
Statistical context
The dossier marks the active-side Primos 3D and dermatologist smoothness findings p<0.05; exact p-values are not published. Self-assessment percentages are descriptive positive-opinion results.
Information checked
2026-08-03

Measured results · 30 days

Primos 3D-measured nasolabial-fold depth

9.5% lower

At day 30, a 2% Ornithine, Phospholipids, and Glycolipids study cream showed 9.5% lower nasolabial-fold depth from baseline by Primos 3D profilometry; the placebo side showed no significant variation.

What was measured
Primos 3D-measured nasolabial-fold depth
When it was measured
30 days

Primos 3D-measured skin roughness

5.9% lower

At day 30, a 2% Ornithine, Phospholipids, and Glycolipids study cream showed 5.9% lower skin roughness from baseline by Primos 3D profilometry; the placebo side showed no significant variation.

What was measured
Primos 3D-measured skin roughness
When it was measured
30 days

Dermatologist clinical score of skin smoothness

31.6% improvement

At day 30, dermatologist clinical scoring found a 31.6% improvement from baseline in skin smoothness on the 2% Ornithine, Phospholipids, and Glycolipids test-cream side (p<0.05).

What was measured
dermatologist clinical score of skin smoothness
When it was measured
30 days

Measured results · 60 days

Dermatologist clinical score of skin smoothness

42.1% improvement

At day 60, dermatologist clinical scoring found a 42.1% improvement from baseline in skin smoothness on the 2% Ornithine, Phospholipids, and Glycolipids test-cream side (p<0.05).

What was measured
dermatologist clinical score of skin smoothness
When it was measured
60 days

Participant feedback · end of 60-day study

Positive opinion that skin was smoother

90% positive opinion

At the end of the 60-day ingredient-combination study, 90% of respondents expressed a positive opinion that skin was smoother.

What was measured
positive opinion that skin was smoother
When it was measured
end of 60-day study

Positive opinion that skin was firmer

90% positive opinion

At the end of the 60-day ingredient-combination study, 90% of respondents expressed a positive opinion that skin was firmer.

What was measured
positive opinion that skin was firmer
When it was measured
end of 60-day study

Positive opinion that skin looked less tired

90% positive opinion

At the end of the 60-day ingredient-combination study, 90% of respondents expressed a positive opinion that skin looked less tired.

What was measured
positive opinion that skin looked less tired
When it was measured
end of 60-day study

Positive opinion that skin was plumper

80% positive opinion

At the end of the 60-day ingredient-combination study, 80% of respondents expressed a positive opinion that skin was plumper.

What was measured
positive opinion that skin was plumper
When it was measured
end of 60-day study

Positive opinion that skin was more lifted

75% positive opinion

At the end of the 60-day ingredient-combination study, 75% of respondents expressed a positive opinion that skin was more lifted.

What was measured
positive opinion that skin was more lifted
When it was measured
end of 60-day study

Positive opinion that the lip contour was smoother

70% positive opinion

At the end of the 60-day ingredient-combination study, 70% of respondents expressed a positive opinion that the lip contour was smoother.

What was measured
positive opinion that the lip contour was smoother
When it was measured
end of 60-day study

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