product guide
Its orchids support resilient-looking skin, and Climate Control carries the yeast-and-kelp bioferment. BlushSense® Cream Blush shows how the technology can join color care, and EyeCrème brings it to dedicated eye-area care. ShadowSense® Eyeshadow carries SenePlex+® too; explore its color film and ingredient care.
SenePlex+® is SeneGence’s foundational proprietary anti-aging complex, at work in most of our products. Our extremophile technology is made with extracts and cells that survive in extreme environments. Its ingredient family combines Calanthe Discolor (Ebine) Extract orchid stem cells and Orchis Mascula (Orchid) Flower Extract; biofermented Saccharomyces Cerevisiae (Yeast) Extract and Laminaria Digitata (Kelp) Extract; Hydrolyzed Opuntia Ficus-Indica (Prickly Pear) Flower Extract; Sodium Hyaluronate, a form of hyaluronic acid; Glucosamine HCl; Urea; Panthenol (vitamin B5); and vitamin E (Tocopheryl Acetate or Tocopherol). SenePlex+® promotes collagen, protects against stressors, brightens the complexion and accelerates skin renewal, while deeply moisturizing skin.
By SeneGence · 
Alan Kante, publisher · Updated
SenePlex+® Technology: Orchid Stem Cells, Bioferments and Hyaluronic Acid for Faster Skin Cell Renewal
The bioferments bring a gently renewed look, the two orchids resilient-looking skin, and prickly pear with humectants moisture and comfort. On Joni Rogers-Kante’s search for extremophile organisms in Vanuatu, the orchid of the Mount Yasur caldera inspired SenePlex+®.
Its orchid stem cell technology (secretomes) includes Calanthe Discolor (Ebine) Extract, our Calanthe discolor orchid stem cells; the yeast-and-kelp bioferments are Saccharomyces Cerevisiae (Yeast) Extract and Laminaria Digitata (Kelp) Extract.
Its orchids support resilient-looking skin, and Climate Control carries the yeast-and-kelp bioferment. BlushSense® Cream Blush shows how the technology can join color care, and EyeCrème brings it to dedicated eye-area care. ShadowSense® Eyeshadow carries SenePlex+® too; explore its color film and ingredient care. DayTime Moisturizer – Normal to Dry and Evening Moisturizer – Normal to Dry are the two moisturizers in the studied SenePlex+® Normal-to-Dry regimen, alongside 3 in 1 Cleanser – Normal to Dry. Explore the SenePlex+ ingredient roles. Detoxifying Oxygen Facial Mask and EyeLuminator™ Under Eye Brightening Cream carry SenePlex+® too, bringing its renewal and moisture care into weekly skincare and sheer morning brightness; see the mask’s complete formula, its Rhodiola and how to use it. Discover the caldera orchid that inspired SenePlex+®.
The orchid of the caldera of the Volcano, Mt. Yasur, on Tanna in Vanuatu inspired SenePlex+®. Joni Rogers-Kante travelled there with scientists to search for what survives harsh conditions, and that search shaped a renewal-minded technology whose complex combines Calanthe Discolor (Ebine) Extract and Orchis Mascula (Orchid) Flower Extract, yeast-and-kelp bioferments and hydrating ingredients. Each SeneGence label shows which of the two orchids that formula carries. Follow Joni’s Vanuatu story.
Microbiome Boosting Serum carries SenePlex+® with orchid stem cells: Calanthe Discolor (Ebine) Extract and Orchis Mascula (Orchid) Flower Extract join yeast-and-kelp bioferments in its prebiotic formula. Explore the Microbiome Boosting Serum formula.
Our blend of clinically proven peptides, exosomes, and proprietary SenePlex+® stem cell technology (secretomes), paired with skin-nourishing botanicals, delivers visible results without unnecessary additives. Beauty Book 2026 (p. 8).