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clinical finding

Palmitoyl Tripeptide-1 — 29-day lip-care study

in the study

Manufacturer study of a Palmitoyl Tripeptide-1 lip-care material

what it showed

The ingredient’s maker reports improved hydration, superficial wrinkles, average lip volume, smoothness, and flaking after 29 days.

You will also find Palmitoyl Tripeptide-1 in LipSense® Long-Lasting Lip Liner Pencil.

In LipSense® Long-Lasting Lip Liner Pencil, Palmitoyl Tripeptide-1 contributes lip hydration, smoothness, and fuller-looking-lip care.

By SeneGence · Alan Kante, publisher · Updated

What supports Palmitoyl Tripeptide-1?

2 details
How it was evaluated
Human instrumental measures, dermatologist assessment, and participant observation without a separate placebo
Who took part
10 women ages 20–40 with thin, small, dry lips
Statistical context
The ingredient’s maker reports changes in hydration, superficial lip wrinkles, average lip volume, smoothness, and flaking after 29 days.
Information checked
2026-09-12

Measured results · day 29

Hydration, superficial wrinkles, and average lip volume

hydration 60% higher, superficial wrinkles 29% lower, and average lip volume 40.7% higher

For the full Ethylhexyl Palmitate, Tribehenin, Sorbitan Isostearate, and Palmitoyl Tripeptide-1 material, the ingredient’s maker reports hydration 60% higher, superficial wrinkles 29% lower, and 40.7% higher average lip volume at day 29 in an uncontrolled 10-woman study of a colorless lipstick containing 1% material, used three times daily.

When it was measured
day 29

Lip condition, smoothness, and flaking

improved lip condition and smoothness with less flaking

For the full Ethylhexyl Palmitate, Tribehenin, Sorbitan Isostearate, and Palmitoyl Tripeptide-1 material, the ingredient’s maker reports that the 10 participants noticed improved lip condition and smoothness with less flaking at day 29 after using the 1% material colorless lipstick three times daily.

When it was measured
day 29