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Choosing products

Which SeneGence products carry peptides, and what do they do?

Quick answer

SeneGence puts peptides where each beauty goal lives: Caprooyl Tetrapeptide-3 in GLP Complex™ and SeneCell™ for smoother-looking lines, a tone-care peptide pair in every DayTime and Evening Moisturizer, Palmitoyl Tetrapeptide-50 with Heptapeptide-15 Palmitate in Lip Line Corrector, and Acetyl Tetrapeptide-3 with clover for fuller-looking brows, lashes and hair. Lip Line Corrector visibly improves the appearance of vertical lip lines by up to 30% after six weeks of twice-daily use in an independent clinical study of 35 women ages 40–70, measured by expert grading against baseline. In an independent study of 31 participants measured by image analysis, GLP Complex™ with SenePlex+® and Exosomes reduced the appearance of deep wrinkles by 11.2% at four weeks and 23.4% at eight weeks, and improved the look of facial volume by 8.4% at eight weeks. Beauty Book 2026 (p. 18).

  • 4 min read

Which peptide serves which beauty goal?

Each peptide is listed by the name you’ll find on the label.
Your goalPeptide (INCI)Where you find itExplore
Smoother-looking lines, firmer-looking skinCaprooyl Tetrapeptide-3 with DextranGLP Complex™ with SenePlex+® and Exosomes, SeneCell™ SenePlex+® StemCell Concentrate and MakeSense® Silk Primer & Pore MinimizerCaprooyl Tetrapeptide-3 ingredient research
Firmer-looking skin with brightening careAcetyl Tetrapeptide-2C-Bright Dark Spot CorrectorWhat C-Bright does
More even-looking tone, lighter-looking dark spotsPalmitoyl sh-Octapeptide-24 Amide with Palmitoyl sh-Tripeptide-5 Norisoleucyl sh-Nonapeptide-1All three DayTime Moisturizers and all three Evening MoisturizersThe tone-care peptide pair
Firming and line care in daytime moistureBis(Tripeptide-1) Copper AcetateDayTime Moisturizer – Dry, Normal to Dry and Normal to OilyThe copper-peptide source
Smoother, firmer, more radiant-looking night careNicotiana Benthamiana Hexapeptide-40 sh-Polypeptide-76Evening Moisturizer – Dry, Normal to Dry and Normal to OilyThe plant-produced peptide study
Multi-factor smoothing and visible renewalsh-Oligopeptide-1, sh-Oligopeptide-2, sh-Polypeptide-1, sh-Polypeptide-9 and sh-Polypeptide-11Advanced SenePlex+® Renewal Serum with RetinolThe five-factor peptide study
Smoother-looking renewalPalmitoyl Tripeptide-1 with Palmitoyl Tetrapeptide-7Advanced SenePlex+® Renewal Serum with RetinolThe facial peptide pair
Softer-looking expression lines, less shineDipeptide Diaminobutyroyl Benzylamide DiacetateNeoTight® Rejuvenating Anti-Wrinkle SerumThe expression-line study
Hydrated, smoother, fuller-looking lipsPalmitoyl Tripeptide-1LipSense® Long-Lasting Lip Liner PencilThe lip peptide study
Smoother-looking lip-area folds, plumper-looking contoursPalmitoyl Tetrapeptide-50 with Heptapeptide-15 PalmitateLip Line Corrector, which improved the look of vertical lip lines in its own clinical studyThe lip-fold study · Beauty Book 2026
Fuller-looking brows, lashes and hairAcetyl Tetrapeptide-3 with Trifolium Pratense (Clover) Flower Extract and DextranBrowSense® Volumizing Brow Gel, HairCovery® Strengthening & Thickening Hair Serum, LashSense® VolumeIntense® Mascara, LashSense® VolumeIntense® Waterproof Mascara and UnderSense® 3-in-1 Maximizing Lash PrimerThe hair and lash studies
Denser, fuller-looking lashesMyristoyl Pentapeptide-17LashExtendThe lash peptide study
Longer-, fuller-, stronger-looking lashesBiotinoyl Tripeptide-1 with PanthenolUnderSense® 3-in-1 Maximizing Lash PrimerLash support
Skin-clarity researchOligopeptide-10UnderSense® 3-in-1 Maximizing Lash PrimerOligopeptide-10 research
A soft-focus setting finishAcetyl Hexapeptide-8Translucent Loose PowderThe peptide research

Peptides are short chains of amino acids, and each one is chosen for a specific visible job. Do peptides work on skin? explains how they fit a routine.

What do SeneGence’s own clinical studies show?

Peptides work inside finished formulas, and SeneGence measures those formulas. Results can also arrive fast. One hour after a single application, NeoTight® Rejuvenating Anti-Wrinkle Serum improved measured net skin elasticity by 7.65% in an independent study. See the GLP Complex study, Beauty Book 2026 (p. 18) and the NeoTight Rejuvenating study. Each peptide in the table links to its ingredient maker’s own research.

How do I build a peptide routine?

  1. For your face, layer Climate Control®, then GLP Complex™, then SeneCell™, then your DayTime or Evening Moisturizer; see the complete skincare order. GLP Complex™.
  2. For lip lines, apply Lip Line Corrector morning and night after cleansing.
  3. For lashes, apply UnderSense®, let it dry fully, then finish with one VolumeIntense® Mascara or VolumeIntense® Waterproof Mascara.

Read the complete peptide guide.

Study results at a glance

Caprooyl Tetrapeptide-3 with Dextran — wrinkle and skin-support studies8 results
Caprooyl Tetrapeptide-3 with Dextran — wrinkle and skin-support studies
ResultKind of resultWhen it was measured
In an in vitro fibroblast assay of Caprooyl Tetrapeptide-3, the ingredient’s maker reports laminin 26% higher and fibronectin 60% higher after 48 hours.Ingredient study48 hours
In a corticoid-stressed four-donor human-skin explant model of Caprooyl Tetrapeptide-3, the ingredient’s maker reports collagen VII staining 34% higher and laminin-5 staining 49% higher versus corticoid alone at day 3.Ingredient studyday 3
In the corticoid-stressed four-donor human-skin explant model, the ingredient’s maker reports that Caprooyl Tetrapeptide-3 helped prevent the dermal-epidermal-junction flattening seen with corticoid alone at day 3.Ingredient studyday 3
The ingredient’s maker reports 16% average improvement in fine-line and wrinkle appearance at day 28 in a randomized split-temple serum study of Glycerin, Water, Dextran, and Caprooyl Tetrapeptide-3.Ingredient studyday 28
In the same randomized split-temple serum study, the ingredient’s maker reports that the full Glycerin, Water, Dextran, and Caprooyl Tetrapeptide-3 material improved fine-line and wrinkle appearance by up to 29% at day 28.Ingredient studyday 28
Show 3 more results
Caprooyl Tetrapeptide-3 with Dextran — wrinkle and skin-support studies, more results
ResultKind of resultWhen it was measured
In the age-defined 50–65 subgroup of the same 27-woman randomized split-temple serum study of the full Glycerin, Water, Dextran, and Caprooyl Tetrapeptide-3 material, the ingredient’s maker reports 27% average and up to 35% improvement in fine-line and wrinkle appearance at day 56.Ingredient studyday 56
In a separate 30-woman self-assessment of a serum with 2.5% of the full Glycerin, Water, Dextran, and Caprooyl Tetrapeptide-3 material used twice daily, the ingredient’s maker reports favorable perceptions of smoothness, firmness, evenness, and a rested look at day 56, plus favorable eye-area tolerability.Participant feedbackday 56
In a 27-woman split-temple ultrasound study of a serum with 2.5% of the full Glycerin, Water, Dextran, and Caprooyl Tetrapeptide-3 material used twice daily, the ingredient’s maker reports improvement versus placebo in 78% of participants on the upper-dermis entropy measure at day 168.Ingredient studyday 168
Who took part
Human instrumental study: 27 women ages 40–65; self-assessment: 30 women ages 40–65; explant work: four human skin specimens
How it was evaluated
In vitro fibroblast work; four-donor stressed skin-explant work; randomized split-temple serum comparisons measured by silicone-replica profilometry and ultrasound; and a 30-woman self-assessment
Statistical context
The manufacturer-authored article reports day-28 wrinkle-appearance improvement in its randomized split-temple serum study.

See the full finding: Caprooyl Tetrapeptide-3 with Dextran — wrinkle and skin-support studies

GLP Complex™ with SenePlex+® and Exosomes — wrinkles and facial-volume study5 results
GLP Complex™ with SenePlex+® and Exosomes — wrinkles and facial-volume study
ResultKind of resultWhen it was measured
In an independent study of 31 participants measured by image analysis, GLP Complex™ with SenePlex+® and Exosomes reduced the appearance of deep wrinkles by 11.2% at four weeks.Measured result4 weeks
All 31 participants showed image-analyzed improvement in deep-wrinkle appearance after four and eight weeks of using GLP Complex™ with SenePlex+® and Exosomes.Measured result4 and 8 weeks
In an independent study, GLP Complex™ with SenePlex+® and Exosomes reduced the appearance of deep wrinkles by 23.4% at eight weeks.Measured result8 weeks
In an independent study, GLP Complex™ with SenePlex+® and Exosomes improved the look of facial volume by 8.4% at eight weeks.Measured result8 weeks
At eight weeks, 81% of participants showed image-analyzed improvement in the look of facial volume after using GLP Complex™ with SenePlex+® and Exosomes.Measured result8 weeks
Who took part
31 participants
How it was evaluated
Image analysis of the finished GLP Complex formula
Statistical context
Deep-wrinkle endpoints p<0.001; facial-volume endpoint at eight weeks p=0.044

See the full finding: GLP Complex™ with SenePlex+® and Exosomes — wrinkles and facial-volume study · Open the study PDF

NeoTight® Rejuvenating Anti-Wrinkle Serum — one-hour and six-week study20 results
NeoTight® Rejuvenating Anti-Wrinkle Serum — one-hour and six-week study
ResultKind of resultWhen it was measured
In an independent study, Rejuvenating Anti-Wrinkle Serum improved measured net skin elasticity by 7.65% one hour after a single application.Measured resultbaseline to 1 hour after a single application
One hour after a single application of NeoTight® Rejuvenating Anti-Wrinkle Serum, expert grading of 31 participants found a 12.05% average improvement in firmer-looking skin.Expert assessment1 hour after a single application
At week 6, 84.38% of participants agreed that they liked how their skin felt immediately after applying Rejuvenating Anti-Wrinkle Serum.Participant feedbackweek-6 questionnaire about immediate application feel
After six weeks of NeoTight® Rejuvenating Anti-Wrinkle Serum, expert grading of 31 participants found a 24.53% average improvement in the appearance of crow’s feet.Expert assessment6 weeks
After six weeks of NeoTight® Rejuvenating Anti-Wrinkle Serum, expert grading of 31 participants found a 13.64% average improvement in the appearance of upper-lip lines.Expert assessment6 weeks
Show 15 more results
NeoTight® Rejuvenating Anti-Wrinkle Serum — one-hour and six-week study, more results
ResultKind of resultWhen it was measured
After six weeks of NeoTight® Rejuvenating Anti-Wrinkle Serum, expert grading of 31 participants found a 7.14% average improvement in the appearance of nasolabial folds.Expert assessment6 weeks
At week 6, 96.88% of participants agreed that Rejuvenating Anti-Wrinkle Serum hydrated their skin well.Participant feedback6 weeks
At week 6, 87.50% of participants agreed that Rejuvenating Anti-Wrinkle Serum improved their skin's overall appearance.Participant feedback6 weeks
At week 6, 84.38% of participants agreed that NeoTight® Rejuvenating Anti-Wrinkle Serum reduced the appearance of fine lines and wrinkles.Participant feedback6 weeks
At week 6, 78.13% of participants agreed that NeoTight® Rejuvenating Anti-Wrinkle Serum reduced the appearance of crow's feet around the eyes.Participant feedback6 weeks
At week 6, 62.50% of participants agreed that NeoTight® Rejuvenating Anti-Wrinkle Serum reduced the appearance of nasolabial folds.Participant feedback6 weeks
At week 6, 71.88% of participants agreed that NeoTight® Rejuvenating Anti-Wrinkle Serum reduced the appearance of upper-lip lines.Participant feedback6 weeks
At week 6, 75.00% of participants agreed that their face appeared more youthful after using Rejuvenating Anti-Wrinkle Serum.Participant feedback6 weeks
At week 6, 75.00% of participants agreed that their skin felt firmer after using Rejuvenating Anti-Wrinkle Serum.Participant feedback6 weeks
At week 6, 71.88% of participants agreed that their skin appeared tighter after using Rejuvenating Anti-Wrinkle Serum.Participant feedback6 weeks
At week 6, 96.88% of participants agreed that their skin tolerated Rejuvenating Anti-Wrinkle Serum well without sensitivities.Participant feedback6 weeks
At week 6, 84.38% of participants agreed that they liked the color, texture, smell, and feel of Rejuvenating Anti-Wrinkle Serum.Participant feedback6 weeks
At week 6, 71.88% of participants agreed that Rejuvenating Anti-Wrinkle Serum absorbed well and did not feel greasy or tacky.Participant feedback6 weeks
At week 6, 87.50% of participants agreed that they liked Rejuvenating Anti-Wrinkle Serum overall.Participant feedback6 weeks
At week 6, 71.88% of participants agreed that they noticed a firmer-looking, more lifted appearance after applying Rejuvenating Anti-Wrinkle Serum.Participant feedbackweek-6 questionnaire about appearance after application
Who took part
n=32 for Cutometer and participant questionnaire; n=31 for expert grading
How it was evaluated
Cutometer MPA 580 R5, expert grading, and participant questionnaire; each endpoint remains separately labeled
Statistical context
Baseline-to-1-hour Cutometer R5 change p=0.015; expert-grading and participant-agreement results are descriptive as reported

See the full finding: NeoTight® Rejuvenating Anti-Wrinkle Serum — one-hour and six-week study · Open the study PDF

Nicotiana fusion peptide — 28-day skin-appearance study10 results
Nicotiana fusion peptide — 28-day skin-appearance study
ResultKind of resultWhen it was measured
For Nicotiana Benthamiana Hexapeptide-40 sh-Polypeptide-76, the ingredient manufacturer reports increased expression of selected genes associated with epidermal lipids and barrier function after 24 and 48 hours in primary human keratinocytes exposed to 20 ng/mL active, stated as 2% material.Ingredient study24 hours; 48 hours
For Nicotiana Benthamiana Hexapeptide-40 sh-Polypeptide-76, the ingredient manufacturer reports dose-responsive collagen I after 48 hours in adult human dermal fibroblasts and describes its assay-specific potency as four times the retinol reference.Ingredient study48 hours
For Nicotiana Benthamiana Hexapeptide-40 sh-Polypeptide-76, the ingredient manufacturer reports qualitative increases in epidermal thickness and lipid staining at day 8 in an exploratory human-skin explant from one 52-year-old donor treated with a cream containing 1.5% material.Ingredient studyday 8
In a 20-woman, placebo-controlled split-face study of Nicotiana Benthamiana Hexapeptide-40 sh-Polypeptide-76, the ingredient manufacturer used a preparation containing 2% material, applied twice daily. At day 28, it reported 16% lower wrinkle count, 11% lower wrinkle volume and 14% lower wrinkle depth across the full study group. Within the separate 85% responder group, wrinkle depth was 19.4% lower on average.Measured resultday 28
For Nicotiana Benthamiana Hexapeptide-40 sh-Polypeptide-76, the ingredient manufacturer reports whole-cohort firmness 11% higher and elasticity 6% higher at day 28 in the 20-woman placebo-controlled split-face study using 2% material twice daily; the 95% responder subsets averaged 12.6% and 6.1% higher.Measured resultday 28
Show 5 more results
Nicotiana fusion peptide — 28-day skin-appearance study, more results
ResultKind of resultWhen it was measured
For Nicotiana Benthamiana Hexapeptide-40 sh-Polypeptide-76, the ingredient manufacturer reports whole-cohort pore diameter 11.6% lower at day 28 in the 20-woman placebo-controlled split-face study; the 80% responder subset averaged 16.2% lower, with improvement up to 44%.Measured resultday 28
For Nicotiana Benthamiana Hexapeptide-40 sh-Polypeptide-76, the ingredient manufacturer reports whole-cohort radiance 12.5% higher at day 28 in the 20-woman placebo-controlled split-face study; the 90% responder subset averaged 14.4% higher, with improvement up to 42%.Measured resultday 28
For Nicotiana Benthamiana Hexapeptide-40 sh-Polypeptide-76, the ingredient manufacturer reports whole-cohort hydration 12.4% higher and transepidermal water loss 9.5% lower at day 28 in the 20-woman placebo-controlled split-face study; hydration had 100% responders, while the 90% water-loss responder subset averaged 11.2% lower.Measured resultday 28
For Nicotiana Benthamiana Hexapeptide-40 sh-Polypeptide-76, the ingredient manufacturer reports whole-cohort skin roughness 6.9% lower at day 28 in the 20-woman placebo-controlled split-face study; the 75% responder subset averaged 12.6% lower, with improvement up to 26%.Measured resultday 28
For Nicotiana Benthamiana Hexapeptide-40 sh-Polypeptide-76, the ingredient manufacturer reports skin thickness 8.0% higher among the 85% responder subset at day 28 in the 20-woman placebo-controlled split-face ultrasound study, with improvement up to 16%.Measured resultday 28
Who took part
Human study: 20 women ages 45–65 using 2% supplier material twice daily for 28 days
How it was evaluated
Keratinocyte and fibroblast assays, a human skin-explant model, and a 20-woman placebo-controlled split-face study using instrumental wrinkle, firmness, pore, radiance, hydration, and water-loss measures
Statistical context
Across the human study, the ingredient manufacturer reports improvements in wrinkles, firmness, radiance, pores, hydration, and water loss at day 28.

See the full finding: Nicotiana fusion peptide — 28-day skin-appearance study · Open the source document (PDF)

Five sh-Oligopeptide and sh-Polypeptide factors in Advanced SenePlex+ Renewal Serum2 results
Five sh-Oligopeptide and sh-Polypeptide factors in Advanced SenePlex+ Renewal Serum
ResultKind of resultWhen it was measured
Using PRIMOS Lite 3D to measure crow’s-feet after use of a cosmetic formula containing sh-Oligopeptide-1, sh-Oligopeptide-2, sh-Polypeptide-1, sh-Polypeptide-9, and sh-Polypeptide-11, the ingredient’s maker reports appearance improvement of 10% at two weeks and 21% at four weeks.Measured resulttwo weeks; four weeks
For the material containing sh-Oligopeptide-1, sh-Oligopeptide-2, sh-Polypeptide-1, sh-Polypeptide-9, and sh-Polypeptide-11, the ingredient’s maker reports a below-eye wrinkle image-analysis measure improved 38% at two weeks and 46% at four weeks.Measured resulttwo weeks; four weeks
Who took part
The public brochure does not disclose sample size, material concentration, comparator, or cadence
How it was evaluated
PRIMOS Lite 3D crow’s-feet measurement and a separate below-eye wrinkle image-analysis measure; public protocol is incomplete
Statistical context
The ingredient’s maker reports improvement in crow’s-feet and a separate below-eye wrinkle measure over four weeks.

See the full finding: Five sh-Oligopeptide and sh-Polypeptide factors in Advanced SenePlex+ Renewal Serum · Open the source document (PDF)

Dipeptide Diaminobutyroyl Benzylamide Diacetate — expression-line study4 results
Dipeptide Diaminobutyroyl Benzylamide Diacetate — expression-line study
ResultKind of resultWhen it was measured
For Dipeptide Diaminobutyroyl Benzylamide Diacetate, the ingredient’s maker reports up to 3.5-fold PLOD3 gene-expression induction after 24 hours in fibroblasts from a 63-year-old donor exposed to the exact peptide; this is an in vitro mechanism endpoint.Measured result24 hours
For Dipeptide Diaminobutyroyl Benzylamide Diacetate, the ingredient’s maker reports statistically significant improvement in forehead wrinkles at day 28 and in mouth-frown lines, upper-lip vertical lines, and forehead gloss at day 7 in a 150-woman placebo-controlled facial study across three skin-tone groups using 4% material twice daily.Ingredient studyday 7 for mouth-frown lines, upper-lip vertical lines, and forehead gloss; day 28 for forehead wrinkles
For Dipeptide Diaminobutyroyl Benzylamide Diacetate, the ingredient’s maker reports day-28 active-cohort agreement for smoother, less shiny, and more beautiful-looking skin across the three skin-tone groups, plus 83% average confidence agreement among 75 users.Participant feedbackday 28
For Dipeptide Diaminobutyroyl Benzylamide Diacetate, the ingredient’s maker reports dose-dependent DPP4 inhibition from 0.8 to 100 ppm in a cell-free biochemical assay.Measured resultassay time not disclosed
Who took part
Human study: 150 women ages 40–64 across three skin-tone groups; active self-assessment subset: 75 participants
How it was evaluated
In vitro gene-expression and biochemical assays; randomized 28-day parallel-group facial study; and active-cohort self-assessment
Statistical context
The manufacturer reports statistically significant improvement in forehead wrinkles at day 28 and in mouth-frown lines, upper-lip vertical lines, and forehead gloss at day 7.

See the full finding: Dipeptide Diaminobutyroyl Benzylamide Diacetate — expression-line study · Open the source document (PDF)

Palmitoyl Tripeptide-1 — 29-day lip-care study2 results
Palmitoyl Tripeptide-1 — 29-day lip-care study
ResultKind of resultWhen it was measured
For the full Ethylhexyl Palmitate, Tribehenin, Sorbitan Isostearate, and Palmitoyl Tripeptide-1 material, the ingredient’s maker reports hydration 60% higher, superficial wrinkles 29% lower, and 40.7% higher average lip volume at day 29 in an uncontrolled 10-woman study of a colorless lipstick containing 1% material, used three times daily.Measured resultday 29
For the full Ethylhexyl Palmitate, Tribehenin, Sorbitan Isostearate, and Palmitoyl Tripeptide-1 material, the ingredient’s maker reports that the 10 participants noticed improved lip condition and smoothness with less flaking at day 29 after using the 1% material colorless lipstick three times daily.Ingredient studyday 29
Who took part
10 women ages 20–40 with thin, small, dry lips
How it was evaluated
Human instrumental measures, dermatologist assessment, and participant observation without a separate placebo
Statistical context
The ingredient’s maker reports changes in hydration, superficial lip wrinkles, average lip volume, smoothness, and flaking after 29 days.

See the full finding: Palmitoyl Tripeptide-1 — 29-day lip-care study

Lip Line Corrector Peptide Pair: What the Palmitoyl Tetrapeptide-50 and Heptapeptide-15 Palmitate Deep-Fold Study Found1 result
Lip Line Corrector Peptide Pair: What the Palmitoyl Tetrapeptide-50 and Heptapeptide-15 Palmitate Deep-Fold Study Found
ResultKind of resultWhen it was measured
For the exact two-peptide material containing Palmitoyl Tetrapeptide-50 and Heptapeptide-15 Palmitate, the ingredient’s maker reports up to 70% lower image-analyzed appearance of deep folds beside the mouth, visible by day 14, in a 28-day study of five adults using 1% material.Measured resultday 14; day 28
Who took part
Five adults ages 49–60
How it was evaluated
Human instrumental image analysis at days 14 and 28
Statistical context
The ingredient’s maker reports visible change by day 14 in its five-adult deep-fold study.

See the full finding: Lip Line Corrector Peptide Pair: What the Palmitoyl Tetrapeptide-50 and Heptapeptide-15 Palmitate Deep-Fold Study Found · Open the source document (PDF)

Acetyl Tetrapeptide-3 with Clover and Dextran — hair and lash studies8 results
Acetyl Tetrapeptide-3 with Clover and Dextran — hair and lash studies
ResultKind of resultWhen it was measured
For the full Butylene Glycol, Water, Dextran, Acetyl Tetrapeptide-3, and Trifolium Pratense (Clover) Flower Extract material, the ingredient’s maker reports follicle elongation 58%, 51%, and 87% higher than untreated follicles at days 4, 7, and 11 in an ex vivo assay of 22 treated and 34 untreated follicles from one donor using 1% material.Measured resultday 4; day 7; day 11
For exact Acetyl Tetrapeptide-3, the ingredient’s maker reports 47% greater elongation than untreated follicles at day 7 in an ex vivo assay of 15 peptide-treated, 27 minoxidil-reference, and 27 untreated follicles; its stated reference comparison belongs only to that assay.Measured resultday 7
For the full Butylene Glycol, Water, Dextran, Acetyl Tetrapeptide-3, and Trifolium Pratense (Clover) Flower Extract material, the ingredient’s maker reports mean anagen density 9% higher, mean telogen density 42% lower, and anagen-to-telogen ratio 88% higher at day 90 in a 23-person baseline-controlled rinse-off scalp study using 1.5% material in shampoo and conditioner every two days.Measured resultday 90
For the full Butylene Glycol, Water, Dextran, Acetyl Tetrapeptide-3, and Trifolium Pratense (Clover) Flower Extract material, the ingredient’s maker reports the two specified Cutibacterium acnes scalp-microbiome ratios 36% and 62% lower at day 90 in 21 people using the rinse-off regimen.Measured resultday 90
For the full Butylene Glycol, Water, Dextran, Acetyl Tetrapeptide-3, and Trifolium Pratense (Clover) Flower Extract material, the ingredient’s maker reports a 15% favorable anagen-density delta, 52% favorable telogen-density delta, and 79-point between-group anagen-to-telogen-ratio delta after four months in a randomized 29-person leave-on scalp study using 5% material nightly.Measured resultfour months
Show 3 more results
Acetyl Tetrapeptide-3 with Clover and Dextran — hair and lash studies, more results
ResultKind of resultWhen it was measured
For the full Butylene Glycol, Water, Dextran, Acetyl Tetrapeptide-3, and Trifolium Pratense (Clover) Flower Extract material, the ingredient’s maker reports up to 27% lash-density improvement with a 93% responder rate at week 8 in a 17-woman split-eye study of a 2.5% material gel versus opposite-eye placebo, used morning and evening.Measured resultweek 8
For the full Butylene Glycol, Water, Dextran, Acetyl Tetrapeptide-3, and Trifolium Pratense (Clover) Flower Extract material, the ingredient’s maker reports 45.5% more new lashes on the active side at week 8 while the placebo side recorded no new lashes in the same 17-woman split-eye study.Measured resultweek 8
For the full Butylene Glycol, Water, Dextran, Acetyl Tetrapeptide-3, and Trifolium Pratense (Clover) Flower Extract material, the ingredient’s maker reports lash length increased by up to 0.70 mm at week 4 in the same 17-woman split-eye study and puts the active-side improvement at three times placebo at week 4 and five times placebo at week 8.Measured resultweek 4; week 8
Who took part
Human studies included 29 leave-on participants, 23 rinse-off participants, 21 microbiome participants, and 17 split-eye lash participants
How it was evaluated
Randomized leave-on scalp study, baseline-controlled rinse-off scalp work, scalp-microbiome analysis, split-eye lash imaging, and ex vivo human-hair-follicle assays
Statistical context
Across distinct studies, the ingredient’s maker reports fuller-looking hair and lashes, scalp-microbiome changes, and follicle elongation.

See the full finding: Acetyl Tetrapeptide-3 with Clover and Dextran — hair and lash studies · Open the source document (PDF)

Myristoyl Pentapeptide-17 — lash-density and keratin-gene studies3 results
Myristoyl Pentapeptide-17 — lash-density and keratin-gene studies
ResultKind of resultWhen it was measured
For Myristoyl Pentapeptide-17, the ingredient’s maker reports induction of hair-specific keratin genes after 48 hours in an in vitro human keratinocyte assay using 0.001% neat material.Ingredient study48 hours
For Myristoyl Pentapeptide-17, the ingredient maker’s conclusion slide reports increasing lash density through day 42, with values of 33.67% at day 14, 46.71% at day 28, and 60.60% at day 42 in a four-person uncontrolled lash-root study testing 5% and 10% supplier-material eyeliner serums once nightly; allocation between strengths and whether or how the conclusion series combines them are not disclosed.Measured resultday 14; day 28; day 42
For Myristoyl Pentapeptide-17, the ingredient’s maker labels a single right-eyelash image series for its 10% supplier-material eyeliner-serum example with increases of 46.26% at day 14, 66.3% at day 28, and 72.29% at day 42.Measured resultday 14; day 28; day 42
Who took part
Human study: four people across 5% and 10% supplier-material conditions; the conclusion slide does not assign its result series to either strength. A separate 10% image sequence is labeled as one example.
How it was evaluated
In vitro human keratinocyte gene-expression assay; uncontrolled four-person lash-root image study; and one separately labeled 10% example image series
Statistical context
The ingredient’s maker reports increasing lash density through day 42 in its four-person study and provides one separately labeled 10% example image series.

See the full finding: Myristoyl Pentapeptide-17 — lash-density and keratin-gene studies · Open the source document (PDF)

Acetyl Hexapeptide-8 — split-face wrinkle studies3 results
Acetyl Hexapeptide-8 — split-face wrinkle studies
ResultKind of resultWhen it was measured
For Acetyl Hexapeptide-8, the ingredient’s maker reports 20.6% lower wrinkle volume and 15.9% lower wrinkle length at day 7 in a randomized split-face placebo study of 22 women using a leave-on cream with 2% supplier solution twice daily.Measured resultday 7
For Acetyl Hexapeptide-8, the ingredient’s maker reports wrinkle roughness 20.4% lower at day 28 in an uncontrolled instrumental study of 18 women using a leave-on cream with 5% supplier solution twice daily.Measured resultday 28
For Acetyl Hexapeptide-8, the ingredient’s maker reports up to 32% lower glutamate release at 2 mM in an in vitro assay.Measured resultassay duration not disclosed
Who took part
Human studies: 22 women in the seven-day split-face study and 18 women in the 28-day study
How it was evaluated
In vitro glutamate-release assay; seven-day randomized split-face placebo comparison; and 28-day uncontrolled instrumental roughness study
Statistical context
The ingredient’s maker reports wrinkle-volume and wrinkle-length changes by day 7 and wrinkle-roughness change by day 28 in its ingredient studies.

See the full finding: Acetyl Hexapeptide-8 — split-face wrinkle studies · Open the source document (PDF)