What does GLP Complex™ do for facial volume and wrinkles?
GLP Complex™ with SenePlex+® and Exosomes is a morning-and-evening facial serum that visibly restores lost facial volume and smooths the look of deep wrinkles, with firmness and glow. GLP means Glow, Lipids and Peptides: Ornithine HCl, Phospholipids and Glycolipids lead its volume-focused care, with plant-derived Centella Asiatica Leaf Vesicles, Caprooyl Tetrapeptide-3 with Dextran and SenePlex+® completing the formula.
By SeneGence · 
Alan Kante, publisher · Updated
Who is GLP Complex for?
Choose GLP Complex™ when cheeks, smile lines or the jawline look less full and deep wrinkles are a priority. SeneGence designed this facial serum for skin affected by aging, weight loss and lifestyle shifts, with care for smoother, firmer, more resilient-looking skin.
GLP stands for Glow, Lipids and Peptides. The pleasure is a softly smoothed face with the look of facial volume; the formula brings several kinds of care together to support that look. Explore GLP Complex on SeneGence.
Which ingredients support the look of facial volume and smoother skin?
Ornithine HCl, Phospholipids and Glycolipids lead the volume-focused care. SeneGence pairs this amino-acid-and-lipid combination to support natural-looking volume where the face may look hollow or depleted.
Centella Asiatica Leaf Vesicles are tiny particles isolated from Centella leaves. We call its Centella ingredient “plant-derived exosomes,” for smoother, firmer, more resilient-looking skin. Its cited exosome research concerns the ingredient technology; those studies did not test the finished SeneGence serum. Read the product’s ingredient description and research qualification. Meet the Centella leaf vesicles.
Caprooyl Tetrapeptide-3 with Dextran contributes care for smoother-looking lines and firmer-looking skin. Explore the Caprooyl Tetrapeptide-3 ingredient research.
SenePlex+® brings its two orchids, Calanthe Discolor (Ebine) Extract, the orchid stem cells, and Orchis Mascula (Orchid) Flower Extract, which brings soothing care, together with Laminaria Digitata (Kelp) Extract and Saccharomyces Cerevisiae (Yeast) Extract, for gentle-looking renewal care.
Glycerin attracts moisture for softness. Sodium Hyaluronate and Sodium Hyaluronate Crosspolymer contribute water-binding hydration; Panthenol and Glucosamine HCl join the conditioning care, while Tocopherol and Tocopheryl Acetate bring Vitamin E into the formula. The serum has a subtle, floral-inspired fragrance. See the complete current formula.
GLP Complex™ combines plumping actives, lipid-replenishing ingredients and peptides to visibly restore lost facial volume and smooth the look of lines.
How does this serum carry SeneGence’s aging intelligently philosophy?
GLP Complex brings SeneGence’s aging-intelligently philosophy to a familiar concern: a face that looks less full even while you are caring for its surface. The formula brings volume-focused lipids together with peptide care, plant-derived vesicles and SenePlex+® for the look of facial volume and a smoother, more resilient-looking finish.
The SenePlex+® thread leads back to Joni Rogers-Kante’s search for life thriving in extremes, where the orchid of the Mount Yasur caldera inspired the technology. GLP Complex™ carries SenePlex+® and that story into your routine. Follow the orchid story into SenePlex+®.
How do I apply GLP Complex?
Give this serum its place morning and evening, pressing gently into the areas where you want the look of facial volume. Follow SeneGence’s current directions:
Apply 2–3 pumps to clean, dry skin morning and evening. Gently press into areas that may look hollow or sagging—like the cheeks, under-eyes, smile lines, and jawline—then smooth over the face and neck. Follow with the rest of your skincare routine.
Where does GLP Complex go in the Triple Cell Renewal Trio?
The Triple Cell Renewal Trio brings together Climate Control, GLP Complex™ with SenePlex+® and Exosomes, and SeneCell™ SenePlex+® StemCell Concentrate. Climate Control prepares with hydration; GLP Complex supplies the volume-and-wrinkle treatment; SeneCell follows with concentrated hydration. Each has a reason to be there.
After cleansing, apply Climate Control, then GLP Complex™, then SeneCell™. Apply EyeCrème, then your moisturizer. That is the order SeneGence gives for this treatment sequence. See the Triple Cell Renewal Trio guide.
For enhanced results, mix GLP Complex™ with Climate Control before applying.
Choose the complete Trio when you want the coordinated preparation and treatment sequence, or see the individual GLP Complex serum when the look of facial volume and smoother deep wrinkles are your current focus. Shop GLP Complex, see Climate Control or see SeneCell.
What did the finished GLP Complex serum study show?
For smoother-looking deep wrinkles and the look of facial volume, the GLP Complex Clinical offers findings from Essex Testing Clinic’s image analysis of the finished serum, compared with baseline. Read the GLP Complex Clinical.
In Essex Testing Clinic’s independent study of 31 participants using GLP Complex™ with SenePlex+® and Exosomes, image analysis found an 11.2% improvement in deep-wrinkle appearance at four weeks compared with baseline.
In an independent study, GLP Complex™ with SenePlex+® and Exosomes reduced deep-wrinkle appearance by 23.4% at eight weeks.
In Essex Testing Clinic’s independent study of 31 participants using GLP Complex™ with SenePlex+® and Exosomes, image analysis found an 8.4% improvement in the look of facial volume at eight weeks compared with baseline.
In Essex Testing Clinic’s independent study, all 31 participants using GLP Complex™ with SenePlex+® and Exosomes showed image-analyzed improvement in deep-wrinkle appearance at four and eight weeks compared with baseline.
In Essex Testing Clinic’s independent study, 81% of the 31 participants using GLP Complex™ with SenePlex+® and Exosomes showed image-analyzed improvement in the look of facial volume at eight weeks compared with baseline.
What can the ingredient studies tell me?
SeneGence pairs volume-focused Ornithine HCl, Phospholipids and Glycolipids with Caprooyl Tetrapeptide-3 and Dextran for the look of facial volume and smoother-looking lines. Ingredient studies explore those materials; the GLP Complex Clinical evaluates the finished serum.
The ingredient’s maker reports 16% average improvement in fine-line and wrinkle appearance at day 28 in a randomized split-temple study of 27 women using a serum containing 2.5% of the Glycerin, Water, Dextran and Caprooyl Tetrapeptide-3 material twice daily, with placebo serum on the opposite temple and measurements made by silicone replicas and interference-fringe profilometry.
The ingredient’s maker reports up to 29% improvement in fine-line and wrinkle appearance at day 28 in a randomized split-temple study of 27 women using a serum containing 2.5% of the Glycerin, Water, Dextran and Caprooyl Tetrapeptide-3 material twice daily, with placebo serum on the opposite temple and measurements made by silicone replicas and interference-fringe profilometry.
Read the complete Caprooyl Tetrapeptide-3 ingredient research. The separate Ornithine, Phospholipids and Glycolipids study tested a study cream containing that ingredient combination. Today’s GLP Complex formula uses Ornithine HCl with Phospholipids and Glycolipids.
Explore the non-peptide actives lesson for more ingredient teaching, or return to the finished GLP Complex serum results.
What does GLP stand for?
GLP means Glow, Lipids and Peptides. GLP Complex™ brings volume-focused lipid care together with peptides, plant-derived Centella leaf vesicles and SenePlex+® for the look of facial volume and smoother, firmer-looking skin.
Are the exosomes plant-derived?
Yes. GLP Complex™ uses Centella Asiatica Leaf Vesicles, tiny particles isolated from Centella leaves, selected for smoother, firmer, more resilient-looking skin.
Which Trio serum goes on first?
After Climate Control, apply GLP Complex™ with SenePlex+® and Exosomes, then SeneCell™ SenePlex+® StemCell Concentrate. Apply EyeCrème, then your moisturizer.
Can I mix GLP Complex with Climate Control?
SeneGence recommends mixing GLP Complex™ with Climate Control before applying for enhanced results. Follow the directed GLP Complex application and the rest of your skincare sequence.
Can I use GLP Complex under the eyes?
The current GLP Complex™ directions include under-eyes among the areas where the face may look hollow or sagging. Gently press into those areas, then smooth over the face and neck. NeoTight™ Eye Serum has its own targeted eye-area directions, including the eyelid.
Did the peptide study test the finished GLP Complex serum?
The Caprooyl Tetrapeptide-3 research tested an ingredient material with Dextran. The GLP Complex Clinical separately evaluated the finished serum’s deep-wrinkle and facial-volume appearance.