Science & Ingredients
Botanical, Marine and Exosome Actives in SeneGence
Explore the botanical extracts, marine ingredients and plant-derived exosomes that help SeneGence formulas hydrate, smooth and improve the look of skin, from the resurrection plant to the Centella leaf vesicles in clinically tested GLP Complex™ with SenePlex+® and Exosomes.
By SeneGence · 
Alan Kante, publisher · Updated
The Exact Name Is Centella Asiatica Leaf Vesicles
GLP Complex™ with SenePlex+® and Exosomes is made for the look of facial volume and smoother-, firmer-, more resilient-looking skin. Ornithine HCl, Phospholipids and Glycolipids lead its volume focus, alongside Caprooyl Tetrapeptide-3 with Dextran and Centella Asiatica Leaf Vesicles.
Vesicles are membrane-bound particles produced by cells; the plant material in this serum comes from centella leaf. Exosomes are a particular subtype of extracellular vesicle, identified by how the cell forms them rather than by size alone. The exact ingredient name here is Centella Asiatica Leaf Vesicles.
how to use it
Find the label name, Centella Asiatica Leaf Vesicles, on GLP Complex™, then apply 2–3 pumps after Climate Control and before SeneCell. Read what the ingredient list confirms, then judge the serum by feel, routine match, and what participants experienced.
the science
In GLP Complex™ with SenePlex+® and Exosomes, the verified INCI is Centella Asiatica Leaf Vesicles: membrane-bound particles derived from Centella asiatica leaf material. The current source establishes the ingredient identity and its place in a formula chosen for smoother-, firmer-, more resilient-looking skin; it does not establish a specific exosome biogenesis pathway or a skin-surface signaling or transport result for the named material.
GLP Complex: Deep-Wrinkle and Facial-Volume Results at 8 Weeks
Deep lines and a face that has lost some of its volume are two different complaints, and most people treat them with two different products. One serum was measured against both.
In an independent study, GLP Complex™ with SenePlex+® and Exosomes reduced the appearance of deep wrinkles by 23.4% at eight weeks.
how to use it
Reach for GLP Complex™ with SenePlex+® and Exosomes when your goal is smoother-looking deep wrinkles or visibly restored facial volume. Apply 2–3 pumps after Climate Control, morning and evening, then let it settle before SeneCell. Ornithine HCl, Phospholipids, and Glycolipids lead the volume focus while Centella vesicles and the rest of the formula complete it.
the science
Independent image analysis in 31 participants measured deep-wrinkle appearance at eight weeks and facial-volume appearance after they used the complete GLP Complex serum. GLP Complex improved deep-wrinkle appearance and the look of facial volume across eight weeks. Ingredient research helps explain why the formula was built this way. GLP Complex Clinical
Plant Vesicles, Peptides, and Botanical Extracts Are Different
Three words get used as though they mean the same thing, and the difference decides which serum you reach for.
Centella Asiatica Leaf Vesicles are plant vesicles, and they are in GLP Complex. Peptides are short amino-acid chains, and a peptide leads NeoTight Rejuvenating Anti-Wrinkle Serum. Botanical extracts keep their own names on the label.
how to use it
On GLP Complex™, find Centella Asiatica Leaf Vesicles; on NeoTight® Rejuvenating Anti-Wrinkle Serum, find the peptide that leads its formula. Then choose by the change you want and follow each serum's own directions.
the science
CENTELLA ASIATICA LEAF VESICLES :: lipid-membrane vesicles from Centella asiatica leaf, the plant-vesicle ingredient in GLP Complex
- PEPTIDE
- a defined amino-acid chain
- BOTANICAL EXTRACT
- a plant-derived ingredient identified by its own INCI
Structure decides the category; vehicle and companion ingredients decide what a formula does with it. When a visible result is the question, use findings from a study of the complete product.
Botanical care for dry skin and a more lifted look
Myrothamnus Flabellifolia (Resurrection) Leaf/Stem Extract comes from the resurrection plant, which survives near-total drying on rock outcrops in southern Africa and revives when water returns; it hydrates, protects and revitalizes stressed skin in DayTime Moisturizer – Dry, also part of the Dry SkinCare Regimen Set. Meet the resurrection plant.
For a firmer, more lifted look, Calanthe discolor orchid stem cells are selected for cosmetic lifting support and a more lifted-looking eye-area appearance. SeneCell and EyeCrème carry Calanthe Discolor (Ebine) Extract. Explore SeneGence orchid stem cells. Read the orchid ingredient study.
Marine ingredients for hydration and an oil-aware finish
Microbiome Boosting Serum contains green seaweed extract, Caulerpa Lentillifera, selected by SeneGence to help reduce an oily look. Fig fruit extract adds moisture-retaining care beside it. Explore Microbiome Boosting Serum.
Irish Moss (Chondrus Crispus Extract) joins hyaluronic acid in a red-seaweed blend for intense, lasting hydration in SeneCell and the Triple Cell Renewal Trio. Digital Age Defense Serum pairs them to hydrate, soften and cool; in GLP Complex, Irish Moss helps condition skin and shape the serum’s texture. Explore SeneCell hydration.
To go deeper on plant-derived exosomes, learn what exosomes are and see what the complete GLP Complex serum achieved.
Study results at a glance
GLP Complex™ with SenePlex+® and Exosomes — wrinkles and facial-volume study5 results
| Result | Kind of result | When it was measured |
|---|---|---|
| In an independent study of 31 participants measured by image analysis, GLP Complex™ with SenePlex+® and Exosomes reduced the appearance of deep wrinkles by 11.2% at four weeks. | Measured result | 4 weeks |
| All 31 participants showed image-analyzed improvement in deep-wrinkle appearance after four and eight weeks of using GLP Complex™ with SenePlex+® and Exosomes. | Measured result | 4 and 8 weeks |
| In an independent study, GLP Complex™ with SenePlex+® and Exosomes reduced the appearance of deep wrinkles by 23.4% at eight weeks. | Measured result | 8 weeks |
| In an independent study, GLP Complex™ with SenePlex+® and Exosomes improved the look of facial volume by 8.4% at eight weeks. | Measured result | 8 weeks |
| At eight weeks, 81% of participants showed image-analyzed improvement in the look of facial volume after using GLP Complex™ with SenePlex+® and Exosomes. | Measured result | 8 weeks |
See the full finding: GLP Complex™ with SenePlex+® and Exosomes — wrinkles and facial-volume study · Open the study PDF
Calanthe discolor orchid stem cells — 56-day eyelid-lift appearance1 result
| Result | Kind of result | When it was measured |
|---|---|---|
| The ingredient’s maker reports a 7.6% eyelid-lift appearance result after 56 days with its Calanthe Discolor-derived material, in a study of 26 women aged 40–65. The material’s eyelid and jawline effects were assessed in two in-vivo studies in women, run separately from SeneGence’s own clinical studies. | Ingredient study | 56 days |
See the full finding: Calanthe discolor orchid stem cells — 56-day eyelid-lift appearance