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clinical finding

SenePlex+ Normal-to-Dry regimen — eight-week skin quality

product or technology studied

SenePlex+® Normal-to-Dry skincare regimen

the finding

Hydration increased 49.99% immediately and remained 28.62% above baseline at week 8, accompanied by broader gains in firmness, radiance, smoothness, tone evenness, and line appearance.

The SenePlex+® Normal-to-Dry skincare regimen increased hydration after the first use, with additional improvements in firmness, radiance, smoothness, tone evenness, and line appearance through Week 8.

For a customer: The results connect an immediate moisture benefit with firmer, smoother, more radiant-looking skin over eight weeks.

updated 2026-08-03 · clinical finding

Week 8 expert grading and consumer agreement. Two clearly separated panels show expert grading endpoints and consumer agreement endpoints for the same Normal-to-Dry three-product regimen.
Measured hydration versus baseline for the Normal-to-Dry regimen. Four separate bars show 49.99 percent immediately, 12.5 percent at week 2, 12.0 percent at week 4, and 28.62 percent at week 8 for the tested three-product regimen.
SenePlex+ Normal-to-Dry regimen measured hydration. Four independent horizontal bars show measured hydration versus baseline for the tested three-product Normal-to-Dry regimen: 49.99 percent immediately, 12.5 percent at week 2, 12.0 percent at week 4, and 28.62 percent at week 8.
SenePlex+ regimen measurement timepoints. Four consistent abstract checkpoint symbols label immediate, week 2, week 4, and week 8 measurements, with result figures presented in the companion chart.
Complete measurements and study notes18 details
How it was evaluated
Eight-week dermatologist-supervised monadic study; Corneometer and Cutometer measurements, expert grading, and consumer questionnaire
Who took part
34 enrolled; 32 completed; women ages 25–70
Statistical context
Hydration p<0.001 at every measured timepoint; expert-grading endpoints statistically significant as reported
Information checked
2026-08-03

Study overview

Skin quality supported by clinical evaluation and consumer agreement

eight-week clinical evaluation and consumer agreement support SenePlex+ for visible skin quality

Eight-week clinical evaluation and consumer agreement support SenePlex+ for visible skin quality.

What was measured
visible skin quality supported by clinical evaluation and consumer agreement
When it was measured
8 weeks

Measured results · after first use

Hydration versus baseline

49.99%

The tested SenePlex+ regimen improved measured hydration by 49.99% immediately after application.

What was measured
measured hydration versus baseline
When it was measured
immediate

Measured results · week 2

Hydration versus baseline

12.5%

The tested SenePlex+ regimen improved measured hydration by 12.5% at week 2.

What was measured
measured hydration versus baseline
When it was measured
2 weeks

Firmness

7.06%

The tested SenePlex+ regimen improved measured firmness by 7.06% at week 2 on the Cutometer R0 parameter, where a lower value indicates firmer skin.

What was measured
measured firmness
When it was measured
2 weeks

Measured results · week 4

Hydration versus baseline

12.0%

The tested SenePlex+ regimen improved measured hydration by 12.0% at week 4.

What was measured
measured hydration versus baseline
When it was measured
4 weeks

Measured results · week 8

Hydration versus baseline

28.62%

The tested SenePlex+ regimen improved measured hydration by 28.62% at 8 weeks.

What was measured
measured hydration versus baseline
When it was measured
8 weeks

Firmness

6.59%

The tested SenePlex+ regimen improved measured firmness by 6.59% at week 8 on the Cutometer R0 parameter, where a lower value indicates firmer skin.

What was measured
measured firmness
When it was measured
8 weeks

Expert assessment · week 8

Brightness, radiance, or luminosity

96.88% of subjects improved

At week 8, expert grading found improved visible brightness, radiance, or luminosity in 96.88% of subjects using the tested regimen.

What was measured
expert-graded visible brightness, radiance, or luminosity
When it was measured
8 weeks

Firmness

80.65% of subjects improved

At week 8, expert grading found improved visible firmness in 80.65% of subjects using the tested regimen.

What was measured
expert-graded visible firmness
When it was measured
8 weeks

Texture and smoothness

71.88% of subjects improved

At week 8, expert grading found improved visible texture or smoothness in 71.88% of subjects using the tested regimen.

What was measured
expert-graded visible texture and smoothness
When it was measured
8 weeks

Tone evenness

56.25% of subjects improved

At week 8, expert grading found improved visible tone evenness in 56.25% of subjects using the tested regimen.

What was measured
expert-graded visible tone evenness
When it was measured
8 weeks

Appearance of fine lines and wrinkles

31.25% of subjects improved

At week 8, expert grading found improvement in the appearance of fine lines or wrinkles in 31.25% of subjects using the tested regimen.

What was measured
expert-graded appearance of fine lines and wrinkles
When it was measured
8 weeks

Mean expert-graded improvement in visible radiance

23.60%

At week 8, expert grading found a 23.60% mean improvement in visible radiance in the tested Normal-to-Dry three-product regimen.

What was measured
mean expert-graded improvement in visible radiance
When it was measured
8 weeks

Participant feedback · week 8

Skin feels more moisturized

100% agreement

At week 8, 100% of subjects agreed that skin felt more moisturized.

What was measured
consumer agreement: skin feels more moisturized
When it was measured
8 weeks

Skin tone looks more supple

100% agreement

At week 8, 100% of subjects agreed that skin tone looked more supple.

What was measured
consumer agreement: skin tone looks more supple
When it was measured
8 weeks

Skin texture feels smoother

100% agreement

At week 8, 100% of subjects agreed that skin texture felt smoother.

What was measured
consumer agreement: skin texture feels smoother
When it was measured
8 weeks

Skin looks more luminous, radiant, or bright

96.88% agreement

At week 8, 96.88% of subjects agreed that skin looked more luminous, radiant, or bright.

What was measured
consumer agreement: skin looks more luminous, radiant, or bright
When it was measured
8 weeks

Consumer purchase intent

96.88% agreement

At week eight, 96.88% of participants said they would buy the Normal-to-Dry 3-in-1 Cleanser, DayTime Moisturizer, and Evening Moisturizer regimen.

What was measured
consumer purchase intent
When it was measured
8 weeks

next step

use this finding in context

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questions this finding answers

  1. ?Is SeneGence clinically tested?answer
  2. ?Does anti-aging skincare actually work?answer
  3. ?What is SenePlex+ and what does it do?answer
  4. ?How long does SeneGence skincare take to work?answer