Hydration, radiance, firmness, and visible surface renewal

SenePlex+ Clinical Results

Two independent studies measured SenePlex+ skincare: the Normal-to-Dry regimen from first use through Week 8, and Evening Moisturizer Normal to Dry in a 20-day surface-renewal study.

Normal-to-Dry regimen · first use to Week 8Evening Moisturizer · 20 daysTwo independent studies

49.99%

immediate increase in hydration

After first use

Normal-to-Dry regimen

23.60%

improvement in visible radiance

Week 8

Normal-to-Dry regimen

Up to 100%

greater visible surface-cell turnover

Day 18

Evening Moisturizer Normal to Dry

Results at a glance

Three SenePlex+ results worth knowing first.

Each diagram names the product or regimen, timing, and result so the two studies stay separate.

SenePlex+ Evening Moisturizer: Up to 100% Greater Visible Surface-Cell Turnover by Day 18. In an independent 20-day study, a tested SenePlex+ Evening Moisturizer formula showed 49% greater visible surface-cell turnover than untreated skin at day 13, 80% at day 16, 94% at day 17, and up to 100% by day 18. Mean full visible surface turnover was 15.5 days at the treated site versus 18.0 days untreated. — SenePlex+ Evening Moisturizer: Up to 100% Greater Visible Surface-Cell Turnover by Day 18

SenePlex+ Regimen Results: Expert Grading and Participant Feedback. Separate panels show week-eight expert grading and week-eight participant agreement for the tested Normal-to-Dry regimen. — SenePlex+ Regimen Results: Expert Grading and Participant Feedback

SenePlex+ Regimen Hydration: First Use Through Week 8. Four horizontal bars show measured hydration improvement for the Normal-to-Dry regimen immediately and at weeks 2, 4, and 8. — SenePlex+ Regimen Hydration: First Use Through Week 8

Normal-to-Dry Regimen: First-Use and 8-Week Results

Hydration increased 49.99% after the first use and remained 28.62% above baseline at Week 8. Visible radiance improved 23.60% at Week 8.

Immediate hydration49.99%

Measured after the first use

Week 8 hydration28.62%

Measured at Week 8

Week 8 expert-graded radiance23.60%

96.88% of participants improved

Week 8 R0 firmness6.59%

Measured at Week 8

What participants noticed at Week 8

100%said skin felt more moisturized.

100%said skin texture felt smoother.

100%said skin tone looked redefined and more supple.

96.88%said skin appeared more luminous, radiant, and bright.

What the eight-week study tested

The study tested 3 in 1 Cleanser, DayTime Moisturizer, and Evening Moisturizer together. The results apply to that three-product Normal-to-Dry regimen, not to one product alone.

Evening Moisturizer Normal to Dry: 20-Day Surface-Renewal Results

In an independent 20-day study, Evening Moisturizer Normal to Dry with SenePlex+ showed up to 100% greater visible surface-cell turnover than untreated skin by Day 18.

Mean time to full visible surface turnover was 15.5 days at treated sites versus 18.0 days at untreated sites. By Day 18, the treated sites had reached complete visible clearance in the study measure.

In 33 participants, treated sites cleared visible surface stain faster than untreated sites throughout the 20-day study.

15.5 vs 18.0

mean days to full visible surface turnover

Treated vs untreated

Evening Moisturizer Normal to Dry

0.00 vs 0.18

residual surface-stain intensity

Day 18 · treated vs untreated

Lower scores mean less residual surface stain.

33

participants completed

20-day study

Treated and untreated sites were compared on each participant.

Measured on the finished moisturizer

The study measured Evening Moisturizer Normal to Dry as a complete formula. It supports this moisturizer’s visible exfoliation result and should not be transferred to every SenePlex+ product.

Study details and sources

The laboratory, products, timing, sample, measurements, and statistical detail for both studies.

Normal-to-Dry regimen laboratoryValidated Claim Support, LLC

Normal-to-Dry regimen reportCS211017 / RE211017.V01

Normal-to-Dry regimen products3 in 1 Cleanser SGF21095-00; DayTime Moisturizer SGF2111-00; Evening Moisturizer SGF21090-01

Normal-to-Dry regimen design8-week single-arm regimen study; 34 enrolled / 32 completed

Evening Moisturizer laboratoryEssex Testing Clinic

Evening Moisturizer panel22107

Evening Moisturizer tested productEvening Moisturizer SGF21090-01

Evening Moisturizer study design20-day treated-site vs untreated-site comparison; 33 completed

Detailed regimen results

Measured outcome	Immediate	Week 2	Week 4	Week 8
Corneometer hydration	+49.99%; p<0.001	+12.54%; p=0.005	+11.98%; p=0.003	+28.62%; p<0.001
Cutometer R0 firmness	-	+7.06%; p=0.016	-	+6.59%; p=0.033
Expert-graded radiance	-	-	-	+23.60%; p<0.001

Hydration increase, firmer R0 readings and expert-graded radiance provide the central regimen results.

Participant experience

Week 8 participant perception	Agreement
Skin feels more moisturized	100%
Skin texture feels smoother	100%
Skin tone looks redefined and more supple	100%
Skin appears more luminous, radiant and bright	96.88%

Self-reported agreement, n=32.

Download the complete study reports

Original source pages follow.

Original reports and evidence records

The complete two-page Essex laboratory summary follows, preserving the laboratory identity, tested formula, study design, full time course and aggregate findings. The VCS regimen study identifiers and aggregate results are presented in the technical section above.

Open the combined report package or inspect either study in its focused evidence record.

Download the combined clinical report (PDF) See the eight-week regimen evidence record See the 20-day surface-renewal evidence record Clinical results

LaboratoryEssex Testing Clinic

Panel22107

Tested formulaEvening Moisturizer SGF21090-01

Study design20-day treated-site comparison

Source authentication

The reproduced Essex Panel 22107 pages retain the original laboratory letterhead and reported study details.

The complete PDF includes the Essex Panel 22107 laboratory pages. One participant code was removed; aggregate findings are unchanged.