What copper peptides does SeneGence use?
Quick answer
SeneGence brings copper to firmer-looking skin two ways: Bis(Tripeptide-1) Copper Acetate, the copper peptide in all three DayTime Moisturizers, and Copper Lysinate/Prolinate, a copper complex paired with Methylglucoside Phosphate in NeoTight® Rejuvenating Anti-Wrinkle Serum. In an independent study, Rejuvenating Anti-Wrinkle Serum improved measured net skin elasticity by 7.65% one hour after a single application. See the NeoTight Rejuvenating results.
- 3 min read
How do the two copper ingredients compare?
| What you want to know | Bis(Tripeptide-1) Copper Acetate | Copper Lysinate/Prolinate | Explore |
|---|---|---|---|
| What it is | A copper peptide. | A copper complex of the amino acids lysine and proline, paired with Methylglucoside Phosphate. | The copper-peptide source · Beauty Book 2026 |
| Where you find it | DayTime Moisturizer – Dry, Normal to Dry and Normal to Oily. | NeoTight® Rejuvenating Anti-Wrinkle Serum. | See every peptide by goal |
| Its beauty job | Firmer-looking skin inside your daily morning moisture. | A plumper, more youthful appearance inside a treatment serum. | NeoTight Rejuvenating results |
Where is the copper peptide?
DayTime Moisturizer – Dry includes Bis(Tripeptide-1) Copper Acetate for firmer-looking skin. This copper-linked peptide also appears in DayTime Moisturizer – Normal to Dry and Normal to Oily; choose the texture for your skin. The ingredient’s maker reports several controlled facial studies of Bis(Tripeptide-1) Copper Acetate for firmer-looking skin and wrinkle care. Read the copper-peptide source. After cleansing, the DayTime Moisturizer for your skin type is your morning moisture step and the base for MakeSense® Original Foundation. Shop DayTime Moisturizer – Dry, DayTime Moisturizer – Normal to Dry or DayTime Moisturizer – Normal to Oily.
Where is the copper complex?
In NeoTight® Rejuvenating Anti-Wrinkle Serum, Copper Lysinate/Prolinate works with Methylglucoside Phosphate beside an expression-line peptide and red algae extract. For a plumper, more youthful appearance, Methylglucoside Phosphate with Copper Lysinate/Prolinate, proline and lysine supports collagen and elastin in NeoTight® Rejuvenating Anti-Wrinkle Serum. Dipeptide Diaminobutyroyl Benzylamide Diacetate smooths the look of fine lines and wrinkles and reduces shine. Porphyridium Cruentum (Red Algae) Extract gives an instant tightening effect. Beauty Book 2026 (p. 18). One hour after a single application of NeoTight® Rejuvenating Anti-Wrinkle Serum, expert grading of 31 participants found a 12.05% average improvement in firmer-looking skin. The finished serum keeps building after the first hour. After six weeks of NeoTight® Rejuvenating Anti-Wrinkle Serum, expert grading of 31 participants found a 24.53% average improvement in the appearance of crow’s feet. See every NeoTight Rejuvenating result. At week 6, 84.38% of participants agreed that NeoTight® Rejuvenating Anti-Wrinkle Serum reduced the appearance of fine lines and wrinkles. Read the NeoTight Rejuvenating clinical report. Apply AM and PM to targeted expression lines. Follow with moisturizer. Beauty Book 2026 (p. 18).
Which one should I choose?
Choose a DayTime Moisturizer when you want copper peptide care inside your everyday morning moisture. Add NeoTight Rejuvenating Anti-Wrinkle Serum when lines, firmness and shine are the focus of a treatment step. They share a routine well: treatment serum first, then moisturizer. One more copper ingredient appears in SeneGence formulas. Copper PCA pairs a mineral with PCA, a component used in moisture-care formulas. SeneSerum-C Hydrating C-Pearls® Serum includes it beside the other PCA mineral salts. See Copper PCA. Explore every SeneGence peptide by goal or whether peptides work on skin.
Study results at a glance
NeoTight® Rejuvenating Anti-Wrinkle Serum — one-hour and six-week study20 results
| Result | Kind of result | When it was measured |
|---|---|---|
| In an independent study, Rejuvenating Anti-Wrinkle Serum improved measured net skin elasticity by 7.65% one hour after a single application. | Measured result | baseline to 1 hour after a single application |
| One hour after a single application of NeoTight® Rejuvenating Anti-Wrinkle Serum, expert grading of 31 participants found a 12.05% average improvement in firmer-looking skin. | Expert assessment | 1 hour after a single application |
| At week 6, 84.38% of participants agreed that they liked how their skin felt immediately after applying Rejuvenating Anti-Wrinkle Serum. | Participant feedback | week-6 questionnaire about immediate application feel |
| After six weeks of NeoTight® Rejuvenating Anti-Wrinkle Serum, expert grading of 31 participants found a 24.53% average improvement in the appearance of crow’s feet. | Expert assessment | 6 weeks |
| After six weeks of NeoTight® Rejuvenating Anti-Wrinkle Serum, expert grading of 31 participants found a 13.64% average improvement in the appearance of upper-lip lines. | Expert assessment | 6 weeks |
Show 15 more results
| Result | Kind of result | When it was measured |
|---|---|---|
| After six weeks of NeoTight® Rejuvenating Anti-Wrinkle Serum, expert grading of 31 participants found a 7.14% average improvement in the appearance of nasolabial folds. | Expert assessment | 6 weeks |
| At week 6, 96.88% of participants agreed that Rejuvenating Anti-Wrinkle Serum hydrated their skin well. | Participant feedback | 6 weeks |
| At week 6, 87.50% of participants agreed that Rejuvenating Anti-Wrinkle Serum improved their skin's overall appearance. | Participant feedback | 6 weeks |
| At week 6, 84.38% of participants agreed that NeoTight® Rejuvenating Anti-Wrinkle Serum reduced the appearance of fine lines and wrinkles. | Participant feedback | 6 weeks |
| At week 6, 78.13% of participants agreed that NeoTight® Rejuvenating Anti-Wrinkle Serum reduced the appearance of crow's feet around the eyes. | Participant feedback | 6 weeks |
| At week 6, 62.50% of participants agreed that NeoTight® Rejuvenating Anti-Wrinkle Serum reduced the appearance of nasolabial folds. | Participant feedback | 6 weeks |
| At week 6, 71.88% of participants agreed that NeoTight® Rejuvenating Anti-Wrinkle Serum reduced the appearance of upper-lip lines. | Participant feedback | 6 weeks |
| At week 6, 75.00% of participants agreed that their face appeared more youthful after using Rejuvenating Anti-Wrinkle Serum. | Participant feedback | 6 weeks |
| At week 6, 75.00% of participants agreed that their skin felt firmer after using Rejuvenating Anti-Wrinkle Serum. | Participant feedback | 6 weeks |
| At week 6, 71.88% of participants agreed that their skin appeared tighter after using Rejuvenating Anti-Wrinkle Serum. | Participant feedback | 6 weeks |
| At week 6, 96.88% of participants agreed that their skin tolerated Rejuvenating Anti-Wrinkle Serum well without sensitivities. | Participant feedback | 6 weeks |
| At week 6, 84.38% of participants agreed that they liked the color, texture, smell, and feel of Rejuvenating Anti-Wrinkle Serum. | Participant feedback | 6 weeks |
| At week 6, 71.88% of participants agreed that Rejuvenating Anti-Wrinkle Serum absorbed well and did not feel greasy or tacky. | Participant feedback | 6 weeks |
| At week 6, 87.50% of participants agreed that they liked Rejuvenating Anti-Wrinkle Serum overall. | Participant feedback | 6 weeks |
| At week 6, 71.88% of participants agreed that they noticed a firmer-looking, more lifted appearance after applying Rejuvenating Anti-Wrinkle Serum. | Participant feedback | week-6 questionnaire about appearance after application |
See the full finding: NeoTight® Rejuvenating Anti-Wrinkle Serum — one-hour and six-week study · Open the study PDF