The SeneGence Review
Get a straight answer about choosing products, building routines, applying LipSense, understanding ingredients and results, or getting to know SeneGence.
Cleanse & remove · Skincare & eye care
Start with the SeneGence Core 4 for your skin type: a cleanser, a daytime moisturizer, an evening moisturizer and EyeCrème, in Dry, Normal to Dry or Normal to Oily, or the Microbiome Collection for oily-to-sensitive skin.
Cleanse & remove · Skincare & eye care
For dry skin, choose the SeneGence Dry Core 4: 3 in 1 Cleanser – Dry, DayTime Moisturizer – Dry, Evening Moisturizer – Dry and EyeCrème.
Moisturize · Skincare & eye care
SeneGence DayTime Moisturizer – Normal to Dry gives lightweight hydration and radiance in a luminous morning finish; Evening Moisturizer – Normal to Dry is the rich night cream that restores moisture and supports natural renewal overnight.
Target & care · Skincare & eye care
Choose GLP Complex™ with SenePlex+® and Exosomes, our volume-restoring serum, to visibly restore lost facial volume, smooth deep wrinkles and firm skin affected by aging, weight loss and lifestyle changes.
Target & care · Skincare & eye care
Choose SeneCell™ SenePlex+® StemCell Concentrate, our anti-aging serum with orchid stem cells, peptides, hyaluronic acid and our highest dose of SenePlex+®, to deliver instant and lasting hydration, visibly lift and firm skin, and help reduce fine lines and wrinkles.
Prepare · Skincare & eye care
Choose Climate Control, our global best-selling preactivated gel essence with SenePlex+®, as your first skincare step after cleansing, morning and evening, to bring even the driest skin long-lasting hydration, leave it looking plump and bouncy, help support collagen and strengthen the skin barrier, and prepare it for the treatments that follow.
Skincare & eye care · Brand-affiliated Reddit discussion
SeneGence Climate Control is a water-light gel essence that hydrates and primes skin right after cleansing; Nangai Oil is a lipid-rich facial oil that seals in moisture when skin still feels dry, tight or depleted. Use Climate Control first, then Nangai Oil after treatments and before DayTime or Evening Moisturizer.
Target & care · Skincare & eye care
SeneGence NeoTight® Rejuvenating Anti-Wrinkle Serum is a targeted facial treatment for firmness, lift and visibly softened lines, with Copper Lysinate/Prolinate and Methylglucoside Phosphate, Dipeptide Diaminobutyroyl Benzylamide Diacetate, Porphyridium Cruentum (Red Algae) Extract and SenePlex+®.
Target & care · Skincare & eye care
SeneGence NeoTight™ Eye Serum is a lightweight morning-and-evening eye treatment for dark circles, puffiness and fine lines, with SenePlex+® (Calanthe Discolor (Ebine) Extract orchid stem cells and Orchis Mascula (Orchid) Flower Extract), Bacillus Ferment and Sodium Hyaluronate (a form of hyaluronic acid) for a firmer, brighter-looking eye area.
Target & care · Skincare & eye care
SeneGence C-Bright Dark Spot Corrector is a feather-light vitamin C treatment that visibly fades dark spots and evens the look of skin tone, built on 3-O-Ethyl Ascorbic Acid with Ferulic Acid, Tocopheryl Acetate, Acetyl Tetrapeptide-2, Sodium Hyaluronate (a form of hyaluronic acid) and SenePlex+®.
Target & care · Skincare & eye care
With SeneGence C-Bright Dark Spot Corrector, our vitamin C treatment for dark spots and hyperpigmentation, look for a first change at two weeks and the full result at eight.
Skincare & eye care
For hyperpigmentation and the look of dark acne marks, choose SeneGence C-Bright Dark Spot Corrector, built on 3-O-Ethyl Ascorbic Acid, a stabilized vitamin C derivative, with Ferulic Acid, Acetyl Tetrapeptide-2 and SenePlex+®.
Skincare & eye care
SeneGence’s Microbiome Collection is the four-step routine for oily-to-sensitive skin: Microbiome Correcting Cleanser, Microbiome Boosting Serum, Microbiome Defense Daytime Moisturizer SPF 15 by day and Microbiome Restorative Evening Moisturizer at night.
Labeled sun protection · Skincare & eye care
After. Sunscreen is the last step of your morning skincare, after serums and moisturizer and before primer and foundation.
Target & care · Skincare & eye care
SeneGence EyeCrème is the nourishing, orchid stem cell-rich eye moisturizer for morning and evening, with Calanthe Discolor (Ebine) Extract and Orchis Mascula (Orchid) Flower Extract in its SenePlex+® and olive-derived Squalane, for a brighter, smoother, more rested-looking eye area.
Color & define · Skincare & eye care
SeneGence EyeCrème is morning-and-evening eye skincare, a rich eye balm of triglyceride-rich oils, olive-derived Squalane and Calanthe discolor orchid stem cells; EyeLuminator™ Under Eye Brightening Cream adds sheer, light-reflecting brightness that you wear alone, under or over makeup.
Moisturize · Skincare & eye care
Choose Nangai Oil, a weightless facial oil from the Nangai tree of Vanuatu, to intensify any daily regimen as it seals in moisture, strengthens the skin barrier and softens the look of fine lines and wrinkles for a youthful glow when skin feels dry, tight or depleted.
Eyes, brows & lashes
What your brows are missing decides the SeneGence BrowSense® format.
Prepare · Eyes, brows & lashes
Yes. A lash primer gives mascara something to grip, so the color that follows lands with more visible volume, length and definition, and SeneGence makes its own.
Color & define · Nails
Apply SeneGence 2-in-1 Base & Top Coat as a base, add two thin coats of SeneGence Nail Polish, letting each dry, then seal with the clear coat for a high-shine, salon-quality finish.
Moisturize · Bath, body & men's grooming
SeneGence Advanced Hydration Body Lotion gives dry skin rich hydration in a light, comfortable finish, with Ceramide NP, shea butter and nourishing seed oils for firmer-looking, radiant skin and no sticky residue.
Daily care · Bath, body & men's grooming
SeneGence Climate Control Body Recovery Mist cools and replenishes body skin after sun, travel or seasonal dryness, with deep-sea Alteromonas Ferment Extract and a red-seaweed hydration blend in a lightweight mist.
Moisturize · Bath, body & men's grooming
SeneGence Reactivating Hand Cream is for hands that are washed often or feel dry through the day: fast-absorbing, non-greasy hydration with ceramide barrier care that you refresh with a little water.
Bath, body & men's grooming
After washing your hands, or whenever they feel dry, lightly dampen the backs of your hands and rub them together: SeneGence Reactivating Hand Cream redistributes and refreshes its hydration, no reapplication needed.
Daily care · Bath, body & men's grooming
SeneGence Fresh Roll-On Deodorant helps with odor rather than stopping sweat: it is an aluminum-free deodorant, not an antiperspirant, and it absorbs perspiration so you stay fresh.
Nails
17-Free means SeneGence Nail Polish is formulated without seventeen commonly avoided nail polish ingredients, from acetone to xylene, while giving richly pigmented, glossy, chip-resistant color you build in two coats.
Moisturize · Skincare & eye care
Refilling your Microbiome Evening Moisturizer saves approximately 96% plastic versus repurchasing the jar.
Moisturize · Skincare & eye care
SeneGence Collagen Firming Night Pak is the marine-based last step of your night: it seals in your evening skincare and helps smooth the look of sleep lines for firmer, smoother, more resilient-looking skin by morning.
Target & care · Skincare & eye care
SeneGence Lifting & Firming Neck Cream is the dedicated neck-and-décolletage treatment that visibly lifts, firms and smooths, with a Calcium Hydroxymethionine and 3-Aminopropane Sulfonic Acid blend, Caffeine and Palmitoyl Carnitine.
Target & care · Skincare & eye care
SeneGence Digital Age Defense Serum helps defend skin against HEV blue light from screens and free-radical damage, with Rosemary and Ethyl Ferulate, a soothing ginger complex and Swiss glacier biotech.
Skincare & eye care
Start with what your skin needs most: choose SeneGence Dry for moisture it can hold on to, Normal to Dry for balanced hydration through the seasons, Normal to Oily for light, oil-balancing hydration, or the Microbiome Collection for oily, sensitive skin.
Skincare & eye care
Choose SeneGence 3 in 1 Cleanser – Dry when skin needs help holding moisture, 3 in 1 Cleanser – Normal to Dry when it shifts with the seasons, 3 in 1 Cleanser – Normal to Oily for oily or combination skin, or Microbiome Correcting Cleanser for oily, sensitive or blemish-prone skin.
Skincare & eye care
Choose the SeneGence DayTime and Evening Moisturizer pair for your skin type, Dry, Normal to Dry or Normal to Oily, or the Microbiome pair for oily, sensitive skin: lightweight, makeup-ready care by day and richer overnight care by night.
Skincare & eye care
Choose SeneGence SeneSerum-C® Hydrating C-Pearls® Serum, with Tetrahexyldecyl Ascorbate, Ergothioneine and Sodium Hyaluronate (a form of hyaluronic acid), for hydrating vitamin C care and an everyday glow; choose C-Bright Dark Spot Corrector, with 3-O-Ethyl Ascorbic Acid, Ferulic Acid and Acetyl Tetrapeptide-2, when dark spots, discoloration and uneven-looking tone lead your decision.
Target & care · Skincare & eye care
Retinol helps skin look brighter and firmer, with less noticeable fine lines over time, and SeneGence Advanced SenePlex+® Renewal Serum with Retinol pairs Retinol and Retinyl Palmitate with Palmitoyl Tripeptide-1 and Palmitoyl Tetrapeptide-7.
Skincare & eye care
Yes. Use SeneGence SeneSerum-C® Hydrating C-Pearls® Serum in the morning and Advanced SenePlex+® Renewal Serum with Retinol at night under Evening Moisturizer, starting every other night and building to nightly use as tolerated.
Skincare & eye care
The skin barrier is your skin’s outermost protective layer, and its lipids help keep water from escaping, which is why a depleted barrier can leave skin feeling tight or uncomfortable. In SeneGence skincare, Microbiome Boosting Serum helps strengthen the skin’s natural barrier, and Microbiome Restorative Evening Moisturizer brings Ceramide NP and Cholesterol for moisture-barrier support.
Skincare & eye care
SenePlex+® is SeneGence’s foundational proprietary anti-aging complex, at work in most of our products. Our extremophile technology is made with extracts and cells that survive in extreme environments. In SenePlex+®, Calanthe discolor orchid stem cells and Orchis Mascula orchid join biofermented yeast and kelp, prickly pear, hyaluronic acid, glucosamine, urea and vitamins B5 and E. SenePlex+® is clinically proven to accelerate skin cell renewal for smoother, brighter, younger-looking skin, and it promotes collagen and protects against everyday stressors.
Skincare & eye care
Skin longevity in skincare means caring for how skin looks and feels over time as its needs change: hydrated, smooth, firm, resilient, even-looking and radiant.
Skincare & eye care
Yes. In SeneGence skincare, plant-derived exosomes work inside GLP Complex™ with SenePlex+® and Exosomes, which carries Centella Asiatica Leaf Vesicles. Its finished-serum study measured improvements in deep-wrinkle and facial-volume appearance.
Skincare & eye care
Yes, when the peptide and the finished formula match the result you want.
Skincare & eye care
Peptides are short chains of amino acids that act as messengers in skincare, each chosen for a specific visible job, such as softer-looking lines or smoother, firmer-looking skin.
Skincare & eye care
Extremophile skincare draws on life that thrives where conditions should destroy it, and for SeneGence the search began in the summer of 2000 at the caldera of the Volcano, Mt. Yasur, on Tanna in Vanuatu.
Skincare & eye care
A resurrection plant can dry out almost completely, then revive when water returns. SeneGence DayTime Moisturizer – Dry carries one, Myrothamnus Flabellifolia (Resurrection) Leaf/Stem Extract, to hydrate, protect and revitalize stressed skin.
Skincare & eye care
Fine volcanic-ash particles help SeneGence Facial Resurfacer polish away dull surface buildup as you massage and rinse, leaving skin smoother and fresher-looking.
Skincare & eye care
Some SeneGence skincare shows results from the first use, and the rest builds over weeks.
Skincare & eye care
“Independently tested” means an outside laboratory evaluated a defined product, ingredient or regimen using a stated method, timeline and visible endpoint.
Face color
Yes. SeneGence builds skincare into its color, and SenePlex+® runs through its skincare and much of its color, so from Climate Control in the morning to removal at night each step prepares skin for the next.
Skincare & eye care
SeneGence brings copper to firmer-looking skin two ways: Bis(Tripeptide-1) Copper Acetate, the copper peptide in all three DayTime Moisturizers, and Copper Lysinate/Prolinate, a copper complex paired with Methylglucoside Phosphate in NeoTight® Rejuvenating Anti-Wrinkle Serum.
Skincare & eye care
SeneGence puts peptides where each beauty goal lives: Caprooyl Tetrapeptide-3 in GLP Complex™ and SeneCell™ for smoother-looking lines, a tone-care peptide pair in every DayTime and Evening Moisturizer, Palmitoyl Tetrapeptide-50 with Heptapeptide-15 Palmitate in Lip Line Corrector, and Acetyl Tetrapeptide-3 with clover for fuller-looking brows, lashes and hair. Lip Line Corrector visibly improves the appearance of vertical lip lines by up to 30% after six weeks of twice-daily use in an independent clinical study of 35 women ages 40–70, measured by expert grading against baseline. In an independent study of 31 participants measured by image analysis, GLP Complex™ with SenePlex+® and Exosomes reduced the appearance of deep wrinkles by 11.2% at four weeks and 23.4% at eight weeks, and improved the look of facial volume by 8.4% at eight weeks.
Skincare & eye care
Plant exosomes are a kind of vesicle: tiny membrane-bound particles that plant cells release. A secretome is the wider set of everything a cell releases. In SeneGence skincare, plant exosomes appear as Centella Asiatica Leaf Vesicles in GLP Complex™ with SenePlex+® and Exosomes, beside Ornithine HCl, Phospholipids, Glycolipids and Caprooyl Tetrapeptide-3.
Skincare & eye care
In the summer of 2000, SeneGence founder Joni Rogers-Kante took scientists and botanists to Mount Yasur, the active volcano on Vanuatu’s Tanna Island, and came back with three discoveries: an ash that clears, an orchid that inspired SenePlex+® renewal and a seed oil that protects.
Color & define · Face color
Choose MakeSense® Original Foundation, our long-lasting, water-resistant liquid foundation with SenePlex+® anti-aging care, for buildable, medium coverage that adapts to your skin tone with a semi-matte, skin-like finish in an oil-free formula.
Color & define · Lips
LipSense® Long-Lasting Liquid Lip Color is SeneGence’s award-winning Global Best Seller.
Target & care · Skincare & eye care
For the look of facial volume after weight loss, SeneGence makes GLP Complex™ with SenePlex+® and Exosomes, a clinically proven serum that visibly restores lost facial volume, smooths deep wrinkles and firms skin affected by aging, weight loss and lifestyle changes.
Skincare & eye care
By week six of an independent study, every participant agreed that SeneGence NeoTight™ Eye Serum nourished the delicate skin around the eyes, and expert grading measured an improved look of dark circles and puffiness.
Skincare & eye care
Choose by what your eye area needs most: SeneGence NeoTight™ Eye Serum for the look of dark circles and under-eye bags, EyeCrème for richer daily moisture and crow’s feet, and EyeLuminator™ Under Eye Brightening Cream for sheer brightness with your makeup.
Skincare & eye care
Layer SeneGence NeoTight™ Eye Serum first and EyeCrème second, both before your moisturizer; tap EyeLuminator™ on in the morning after skincare, then add Corrective Color Concealer only where you want more coverage.
Skincare & eye care
Apply SeneGence skincare in this order: cleanse, then Climate Control®, then treatments from lightest to richest (for the Triple Cell Renewal Trio, GLP Complex™ with SenePlex+® and Exosomes, then SeneCell™ SenePlex+® StemCell Concentrate), then NeoTight™ Eye Serum and EyeCrème, then Nangai Oil when skin feels dry, and finish with the moisturizer for that time of day.
Skincare & eye care
Serum goes on before moisturizer. In the SeneGence order, cleanse, then use Climate Control®, GLP Complex™, SeneCell™, Nangai Oil when skin feels dry, and the moisturizer for your skin type and time of day.
Moisturize · Skincare & eye care
Use both because SeneGence built each for its time of day: DayTime Moisturizer – Dry gives lightweight morning moisture and a smooth base for makeup, and Evening Moisturizer – Dry is a richer night cream for overnight care. Both share a peptide pair for more even-looking tone.
Color & define · Lips
Yes. LipSense® lip color is safe for everyday use as directed, and SeneGence tests its products for safety, quality and performance before they reach you.
Lips
SeneGence LipSense® Color is built from a quick-drying Alcohol Denat. carrier, a flexible long-wear film, shade pigments and soothing botanicals, and Moisturizing Gloss seals it with Shea Butter, vitamin E and Glycerin.
Skincare & eye care
Fermented ingredients are made when bacteria, yeasts or fungi transform a plant or other source, and in SeneGence skincare each one has its own job: Lactobacillus Ferment conditions dry-looking skin for a supple feel, and filtered yeast ferment helps a formula hold on to water.
Skincare & eye care
To help a damaged skin barrier recover, keep the routine gentle: SeneGence Microbiome Correcting Cleanser cleanses while preserving the barrier, Microbiome Boosting Serum helps strengthen the skin’s natural barrier, and Microbiome Restorative Evening Moisturizer seals in ceramides and cholesterol overnight.
Skincare & eye care
Start by making your routine gentler: cleanse gently, stop over-cleansing and harsh or antibacterial washes, add hydration where skin feels tight, and change one step at a time. SeneGence’s Microbiome Collection is built for that reset.
Exfoliate & mask · Skincare & eye care
SeneGence Facial Resurfacer pairs walnut shell powder with volcanic ash from Mount Yasur, selected for a fine, near-spherical particle profile, to polish and exfoliate without irritation.
Skincare & eye care
Skincare pilling is when layered products ball up into little rolls instead of settling into an even film.
Color & define · Face color
Choose SeneGence MakeSense® Color Correcting Tinted Moisturizer (CCTM) for breathable, sheer-to-medium correction that helps visibly neutralize redness and uneven tone with a natural-looking radiant finish; choose MakeSense® Original Foundation for more buildable coverage with a semi-matte, skin-like finish. You don’t have to choose: wear CCTM alone, or layer Original Foundation over it wherever you want more coverage.
Cleanse & remove · Lips
To remove long-wear SeneGence makeup, match the remover to the zone: Fooops!® Dual Phase Color Remover for face and eye color, including ShadowSense® Eyeshadow and waterproof LashSense® mascara; Ooops!™ Lip Color Remover for LipSense®; and Melt-Away Deep Cleansing Balm to melt off a full face as your first cleanse.
Lips
The Permeable Polymer Matrix is the breathable, flexible color film in SeneGence’s LipSense® Long-Lasting Liquid Lip Color: three thin layers set into one film, and because the film is permeable, the conditioners in LipSense® Moisturizing Gloss pass through it to the lips beneath.
Skincare & eye care
Many SeneGence formulas are made with sensitive skin in mind.
Skincare & eye care
Yes. SeneGence EyeCrème, EyeLuminator™ Under Eye Brightening Cream, Fooops!® Dual Phase Color Remover and Fooops!® Color Removing Wipes are all ophthalmologist-tested and safe for contact-lens wearers; apply each around the eye, never in it.
Color & define · Lips
LipSense® Long-Lasting Liquid Lip Color is SeneGence’s long-lasting liquid lipstick. Compared with conventional one-tube liquid lipsticks, it uses a three-piece system: three thin layers of Liquid Lip Color, LipSense Moisturizing Gloss on top, and Ooops!™ Lip Color Remover to take it off.
Lips
A brief tingle or mild burning feeling when you apply SeneGence LipSense® Long-Lasting Liquid Lip Color comes from its fast-drying alcohol base evaporating as the color film sets, and dry or unconditioned lips feel it more.
Lips · Brand-affiliated Reddit discussion
It doesn’t have to. SeneGence LipSense® pairs long-wear color with conditioning: three thin layers of Liquid Lip Color set into a breathable film, and LipSense Moisturizing Gloss on top conditions the lips beneath.
Color & define · Lips
Choose SeneGence LipSense® Long-Lasting Liquid Lip Color for extended, customizable wear from three thin layers sealed with Moisturizing Gloss, or LipSense® Cream (formerly HydraMatte) when one-step, Gloss-free color leads.
Color & define · Lips
SeneGence LipSense Long-Lasting Liquid Lip Color offers waterproof, kiss-proof, transfer-proof wear for up to 18 hours.
Color & define · Lips
Apply LipSense® Long-Lasting Liquid Lip Color, SeneGence's long-lasting liquid lipstick, in three thin layers on clean, dry lips, letting each set, then seal with LipSense® Moisturizing Gloss.
Cleanse & remove · Lips
To remove SeneGence LipSense®, dip the Ooops!™ Lip Color Remover wand, gently rub the applicator over the color, and wipe clean with tissue.
Color & define · Lips
SeneGence LipSense® usually looks patchy or flakes when balm or oil is left on the lips, layers go on too thickly, or strokes go back and forth; take it off with Ooops!™ Lip Color Remover and rebuild in thin layers.
Finish · Lips
Start with a sheer neutral SeneGence LipSense® Moisturizing Gloss, Glossy, Pearl or Satin Matte, so your LipSense® shade reads true, then add lightly tinted, richly tinted or glitter Glosses to transform the look without buying a new color.
Finish · Lips
Yes, within the SeneGence line. Seal LipSense® Color with LipSense® Moisturizing Gloss once the third layer has set, and Glowify® Juicy Plumping Lip Gloss is also directed for wear over LipSense®; glosses made outside the LipSense system can soften the color film.
Lips
Choose SeneGence Glowify® Sheer Silk Lip Oil for cushiony hydration and soft blur on bare lips, or Glowify® Juicy Plumping Lip Gloss for a cooling feel and visibly fuller-looking lips, worn bare or over LipSense®.
Color & define · Lips
Choose the SeneGence LipSense® Long-Lasting Lip Liner Pencil, which replaced the earlier liquid liner.
Color & define · Face color
Choose SeneGence Glowify® ColorSense Multi-Use Cream Pigment for bold, opaque matte color on lips or cheeks that wears water-resistant and smudge-proof all day, or Glowify® Bouncy Mousse Multi-Use Pigment for sheer, dewy, buildable color across cheeks, lips and eyes.
Color & define · Eyes, brows & lashes
Choose SeneGence Glowify® Long-Lasting Eyeshadow Stick for a quick, one-swipe soft-focus shimmer wash, or ShadowSense® Eyeshadow for highly pigmented matte-to-shimmer color you blend with its doe-foot before it sets; both set to waterproof, crease-resistant wear.
Prepare · Face color
SeneGence Glowify® Microbiome Serum Primer is skincare and glow in one step: it hydrates and conditions, helps balance excess oil and leaves a soft-focus, lit-from-within radiance on its own or under foundation.
Color & define · Face color
SeneGence’s Pearlizer Highlighter Wand is a swipe-on cream highlighter made for radiance that lasts all day.
Color & define · Face color
Yes. Wear SeneGence Corrective Color Concealer alone for targeted correction where you want it. Tap and blend with a brush, sponge or clean fingertip, building thin layers as needed; add MakeSense® Color Correcting Tinted Moisturizer or MakeSense® Original Foundation when you want a more perfected overall finish.
Color & define · Face color
For soft sculpting, trace MakeSense® Contouring Bronzer Cream under the cheekbones, along the jawline and at the sides of the nose. For radiant warmth, blend it across the forehead, temples and cheeks. Start lightly, build as you like, and blend upward and outward.
Target & care · Eyes, brows & lashes
SeneGence LashExtend is a lightweight lash-line serum built around the peptide Myristoyl Pentapeptide-17.
Lips
Choose SeneGence LipSense® Moisturizing Lip Balm to hydrate and comfort bare lips with a matte finish, Lip Line Corrector for smoother-looking lines around the mouth, or Overnight Lip Mask for softer, fuller-looking lips by morning.
Yes. SeneGence is an established skincare and cosmetics company founded by Joni Rogers-Kante, with its own product-development lab, manufacturing operations and published clinical reports.
Yes. Every SeneGence product is rigorously tested for safety, quality and proven performance before it reaches your skin, and our skincare is dermatologist tested.
SeneGence's orchid stem cells are Calanthe Discolor (Ebine) Extract, plant stem cells from the Ebine orchid at the heart of SenePlex+®, chosen for a firmer, more lifted look in our vegan skincare formulas.
Yes. SeneGence uses hyaluronic acid throughout its skincare. Sodium Hyaluronate is part of SenePlex+®, our foundational proprietary complex featured in most SeneGence products, and it attracts and retains moisture for plumper-looking skin and a reduced look of aging signs.
Target & care · Skincare & eye care
Choose GLP Complex™ with SenePlex+® and Exosomes for lost facial volume and deep wrinkles; choose SeneCell™ SenePlex+® StemCell Concentrate for lightweight, layerable hydration and our highest dose of SenePlex+®.
Daily care · Wellness & oral care
Choose VitaSense™ Sleep Supplement to help you relax, fall asleep more easily, enjoy sound sleep and wake up feeling refreshed, with organic Ashwagandha, immediate- and extended-release Melatonin and Magnesium Glycinate.*
Color & define · Lips
LipSense® is SeneGence’s flagship long-lasting liquid lipstick, a wax-free color that sets on your lips as a flexible, breathable film and holds until you take it off.
Color & define · Eyes, brows & lashes
Choose SeneGence LashSense® VolumeIntense® Mascara to build lash volume, LashSense® FiberExtend Mascara for a natural-looking false-lash effect, or LashSense® VolumeIntense® Waterproof Mascara for waterproof wear.
Skincare & eye care
The SeneGence Triple Cell Renewal Trio pairs Climate Control, GLP Complex™ with SenePlex+® and Exosomes, and SeneCell™ SenePlex+® StemCell Concentrate for preparation, lost facial volume and deep-wrinkle care, and concentrated hydration.
Skincare & eye care
The SeneGence Normal-Oily SkinCare Regimen Set brings together 3 in 1 Cleanser – Normal to Oily, EyeCrème, DayTime Moisturizer – Normal to Oily and Evening Moisturizer – Normal to Oily, each made with SenePlex+®, to cleanse and refine pores, care for the eye area, give lightweight, mattifying moisture by day and nourish skin at night.
Moisturize · Skincare & eye care
DayTime Moisturizer – Normal to Oily gives lightweight, mattifying moisture for daytime and makeup; Evening Moisturizer – Normal to Oily nourishes skin overnight. Together, the pair gives normal-to-oily skin SeneGence care morning and night.
Target & care · Skincare & eye care
SeneGence SeneSerum-C® Hydrating C-Pearls® Serum is a hydrating vitamin C serum that brightens, hydrates and firms skin while protecting it against environmental free radicals.
Target & care · Skincare & eye care
SeneGence Advanced SenePlex+® Renewal Serum with Retinol is our nighttime retinol serum made with SenePlex+®, and it supports a visible reduction in fine lines and wrinkles, smooths texture and refines tone overnight, and helps support firmness and hydration.
Color & define · Eyes, brows & lashes
SeneGence LashSense® VolumeIntense® Mascara is a buildable volume mascara and one of our Global Best Sellers, made to take your lashes to 3-D intensity and dramatic volume. LashSense® VolumeIntense® Mascara gives all-day, smudge- and budge-proof wear. Build the formula for your preferred lash volume while conditioning and helping strengthen lashes over time.
Kiss & Tell Rewards is SeneGence’s free customer loyalty program: you earn rewards every time you shop, share or engage, then redeem your points for dollars off future purchases or free products.
Target & care · Skincare & eye care
Choose Microbiome Boosting Serum, a lightweight SenePlex+® serum for all skin types, with hyaluronic acid and pre- and probiotics, to hydrate and help strengthen the skin's natural microbiome and barrier for calmer, healthier-looking, more resilient skin with a youthful glow, in any routine, morning and evening.
Exfoliate & mask · Skincare & eye care
SeneGence Detoxifying Oxygen Facial Mask turns from gel into a foam of tiny bubbles to draw out impurities and excess oil, remove dead skin cells and reveal smoother, more radiant skin.
Color & define · Eyes, brows & lashes
Choose ShadowSense® Eyeshadow, our long-lasting cream eyeshadow with SenePlex+®, for highly pigmented crème-to-powder color you blend, then let set to a waterproof, smudge-proof, crease-free finish.
Target & care · Lips
SeneGence Lip Line Corrector is a targeted treatment for the delicate lip contour, pairing encapsulated peptide complexes with SenePlex+® stem cell technology to visibly smooth vertical lip lines and enhance lip definition.
Try SeneGence shades virtually, use undertone guidance to narrow your choices, then check MakeSense® Original Foundation across your jaw and neck in natural daylight.
Color & define · Eyes, brows & lashes
Choose SeneGence EyeSense® Long-Lasting Eye Liner Pencil for blendable definition and waterline use, EyeSense® Liquid Eyeliner Pen for felt-tip precision, or EyeSense® Long-Lasting Liquid Eye Liner for brush-applied shimmer.
Yes. Men can use SeneGence skincare chosen by skin type and concern: a 3 in 1 Cleanser, Climate Control, DayTime and Evening Moisturizer, and treatments such as SeneCell™ SenePlex+® StemCell Concentrate or GLP Complex™ with SenePlex+® and Exosomes, made with SenePlex+®, SeneGence’s foundational proprietary anti-aging complex.
Skincare & eye care
No. SeneGence formulates without parabens, SLS (sodium lauryl sulfate) and PFAS.
In Oklahoma. SeneGence manufactures its products; its manufacturing and fulfillment operations are located in west Tulsa, Oklahoma.
SeneGence, pronounced “sen-eh-jens,” stands for four pillars.
Target & care · Hair & scalp
Yes, over time. Choose HairCovery® Strengthening & Thickening Hair Serum, our leave-in serum, to strengthen hair with SenePlex+® and enhance hair thickness by adding volume, for thicker-looking hair with shine and a silky finish, while it supports a balanced scalp microbiome.
Hair & scalp
Choose SeneGence HairBalance® Shampoo and Scalp & Hair Serum for oily-looking roots and buildup, HairPlenish® Scalp & Hair Serum for dry or frizz-prone hair that needs softness and shine, and HairCovery® Strengthening & Thickening Hair Serum for fine, flat or thinning-looking hair that you want to look thicker and fuller over time.
Wellness & oral care
Yes. VitaSense™ Beauty + Collagen is no longer available from SeneGence. It was a strawberry-lemonade dietary supplement powder with 2.5 grams of responsibly sourced Type I hydrolyzed marine collagen peptides in each serving.
Daily care · Wellness & oral care
Choose SeneGence Sweet Relief Spray with Magnesium & SenePlex+ to mist your body or linens as you wind down, or Sweet Relief Stick with Magnesium & SenePlex+ to apply the same calming aromatherapy to your temples, neck, wrists or the balls of your feet. Both pair Magnesium Chloride with peppermint, lavender, copaiba and sweet basil to help promote relaxation as part of a calming bedtime routine.
Yes. You can buy SeneGence as a retail customer or join Kiss & Tell Rewards, our Preferred Customer program; either way you are simply a customer, with nothing to sell and no business to join.
You can buy SeneGence online at senegence.com, our online store, or through our shoppable Beauty Book 2026.
No. FDA does not pre-approve finished cosmetics such as SeneGence LipSense®.
The SeneGence Mechanical Shield is a three-layer complexion technique: the DayTime Moisturizer for your skin type, then MakeSense® Silk Primer & Pore Minimizer, then MakeSense® Original Foundation, so moisture, a soft-focus base and buildable coverage wear as one finish.
SeneGence joins senescence, the natural process of aging, with intelligence, the power to learn, adapt and innovate, and together they name the idea of aging intelligently.
Lips
Yes. SeneGence spends where you can feel it, on long-wear color, on skincare tested in independent studies, and on the formula instead of a box you would throw away.
SeneGence builds skincare into its long-wear color, so every hour you wear it is an hour it works for you.
How SeneGence works today, its shopping avenues and customer guarantees.
How SeneGence works today, its shopping avenues and customer guarantees.
Lips
Joni Rogers-Kante is the Founder, CEO and Chairwoman of SeneGence, the high-performance skincare and cosmetics company she started in 1999 as a single mother with no investment capital and one idea: kiss-proof lip color.
Lips
SeneGence was founded in 1999 and marks 27 years in business in 2026.
Skincare & eye care
Yes. SeneGence tests its finished formulas in independent clinical studies, and the results are specific.
Skincare & eye care
Aging intelligently is the SeneGence philosophy behind its name: “Sene” from senescence, the natural process of aging, and “Gence” from intelligence, the power to learn and adapt.
Skincare & eye care
Yes. SeneGence makes Clean Beauty a formulation choice: We formulate to the European Union cosmetic standard, which prohibits 1,700+ substances.
Yes. SeneGence formulas are gluten-free: everything we make, from LipSense® to our anti-aging skincare, is formulated without gluten-containing ingredients.
Yes. SeneGence is cruelty-free and never tests on animals. All topical products are vegan-friendly, and everything is formulated without gluten-containing ingredients.
Skincare & eye care
Yes. Tested SeneGence formulas show visible results on their own study timelines.
Yes, SeneGence has chosen from the start to leave the retail outer carton off its products, and it holds what it leaves behind to the same standard as its anti-aging skincare and color cosmetics.
Your product arrived without a box because SeneGence deliberately leaves off the printed retail outer carton—the bottle is not missing a piece. SeneGence reports that more than 1.2 million individual retail outer cartons were not used from the start of tracking in 2002 through its latest responsibility report (2026 edition).
The Make Sense Foundation is the nonprofit SeneGence founder Joni Rogers-Kante established to support women and children in need, through scholarships, nonprofit grants, in-kind product donations, fundraising, community partnerships and service.
