Why Use Both SeneGence Dry DayTime and Evening Moisturizers?

Q: How do the Dry day and night moisturizers divide the work?

Both share a tone-care peptide pair and orchid stem cells; texture, timing and the rest of each formula suit a different time of day. What you want to know DayTime Moisturizer – Dry Evening Moisturizer – Dry Explore When and how it feels Mornings, with lightweight moisture and a lighter finish under MakeSense® Original Foundation. Nights, as a thick, richer cream for overnight care after cleansing. Build the Dry skincare routine Both formulas Calanthe Discolor (Ebine) Extract (orchid stem cells), Lactic Acid/Glycolic Acid Copolymer, the hyaluronates and the peptide pair Palmitoyl sh-Octapeptide-24 Amide with Palmitoyl sh-Tripeptide-5 Norisoleucyl sh-Nonapeptide-1. The same shared ingredients, with the orchid stem cells for the look of sagging skin. The shared tone-care peptides Only in this formula Bis(Tripeptide-1) Copper Acetate for firmer-looking skin, Myrothamnus Flabellifolia (Resurrection) Leaf/Stem Extract and Squalane. Nicotiana Benthamiana Hexapeptide-40 sh-Polypeptide-76 for texture and radiance, Niacinamide for the look of pores, and Laminaria Digitata and Saccharomyces Cerevisiae ferments. DayTime copper peptide · Evening third peptide Oils, butter and moisture Glycerin and Aloe Barbadensis (Aloe Vera) Leaf Juice in a lightweight base. Canarium Indicum (Nangai) Seed Oil, Limnanthes Alba (Meadowfoam) Seed Oil, Carthamus Tinctorius (Safflower) Seed Oil and Butyrospermum Parkii (Shea) Butter, with additional SenePlex+®. Evening SenePlex+ formula information DayTime Moisturizer – Dry carries SenePlex+® with Calanthe Discolor (Ebine) Extract, our orchid stem cells, and adds Myrothamnus Flabellifolia (Resurrection) Leaf/Stem Extract from the resurrection plant, a true extremophile. Official DayTime formula and directions.

Q: What do both Dry moisturizers share?

Both formulas carry Palmitoyl sh-Octapeptide-24 Amide and Palmitoyl sh-Tripeptide-5 Norisoleucyl sh-Nonapeptide-1, with Calanthe Discolor (Ebine) Extract from Calanthe discolor orchid stem cells, Lactic Acid/Glycolic Acid Copolymer and several hyaluronic-acid ingredients. The ingredient manufacturer designed this two-peptide system, Palmitoyl sh-Octapeptide-24 Amide with Palmitoyl sh-Tripeptide-5 Norisoleucyl sh-Nonapeptide-1, for more even-looking tone and lighter-looking dark spots. It also reports a 56-day study of the pair. Read the ingredient maker’s two-peptide research.

Quick answer

Use both because SeneGence built each for its time of day: DayTime Moisturizer – Dry gives lightweight morning moisture and a smooth base for makeup, and Evening Moisturizer – Dry is a richer night cream for overnight care. Both share a peptide pair for more even-looking tone.

By SeneGence · Alan Kante, publisher · Updated October 30, 2026

DayTime vs. Evening Moisturizer – Dry: what each one carries — The Dry pair shares its core care; DayTime adds the resurrection plant, and Evening adds richer overnight care. DayTime Moisturizer – Dry and Evening Moisturizer – Dry share Calanthe Discolor (Ebine) Extract and a peptide pair; DayTime adds Myrothamnus and a copper peptide under makeup, Evening adds a Nicotiana peptide, Niacinamide and rich oils overnight.

How do the Dry day and night moisturizers divide the work?

Both share a tone-care peptide pair and orchid stem cells; texture, timing and the rest of each formula suit a different time of day.
What you want to know	DayTime Moisturizer – Dry	Evening Moisturizer – Dry	Explore
When and how it feels	Mornings, with lightweight moisture and a lighter finish under MakeSense® Original Foundation.	Nights, as a thick, richer cream for overnight care after cleansing.	Build the Dry skincare routine
Both formulas	Calanthe Discolor (Ebine) Extract (orchid stem cells), Lactic Acid/Glycolic Acid Copolymer, the hyaluronates and the peptide pair Palmitoyl sh-Octapeptide-24 Amide with Palmitoyl sh-Tripeptide-5 Norisoleucyl sh-Nonapeptide-1.	The same shared ingredients, with the orchid stem cells for the look of sagging skin.	The shared tone-care peptides
Only in this formula	Bis(Tripeptide-1) Copper Acetate for firmer-looking skin, Myrothamnus Flabellifolia (Resurrection) Leaf/Stem Extract and Squalane.	Nicotiana Benthamiana Hexapeptide-40 sh-Polypeptide-76 for texture and radiance, Niacinamide for the look of pores, and Laminaria Digitata and Saccharomyces Cerevisiae ferments.	DayTime copper peptide · Evening third peptide
Oils, butter and moisture	Glycerin and Aloe Barbadensis (Aloe Vera) Leaf Juice in a lightweight base.	Canarium Indicum (Nangai) Seed Oil, Limnanthes Alba (Meadowfoam) Seed Oil, Carthamus Tinctorius (Safflower) Seed Oil and Butyrospermum Parkii (Shea) Butter, with additional SenePlex+®.	Evening SenePlex+ formula information

DayTime Moisturizer – Dry carries SenePlex+® with Calanthe Discolor (Ebine) Extract, our orchid stem cells, and adds Myrothamnus Flabellifolia (Resurrection) Leaf/Stem Extract from the resurrection plant, a true extremophile. Official DayTime formula and directions.

Both formulas carry Palmitoyl sh-Octapeptide-24 Amide and Palmitoyl sh-Tripeptide-5 Norisoleucyl sh-Nonapeptide-1, with Calanthe Discolor (Ebine) Extract from Calanthe discolor orchid stem cells, Lactic Acid/Glycolic Acid Copolymer and several hyaluronic-acid ingredients. The ingredient manufacturer designed this two-peptide system, Palmitoyl sh-Octapeptide-24 Amide with Palmitoyl sh-Tripeptide-5 Norisoleucyl sh-Nonapeptide-1, for more even-looking tone and lighter-looking dark spots. It also reports a 56-day study of the pair. Read the ingredient maker’s two-peptide research.

What does DayTime Moisturizer – Dry do in the morning?

DayTime adds a copper peptide and a Resurrection plant extract in a lightweight formula that replenishes moisture, helps brighten and even tone, and reduces the appearance of fine lines and wrinkles. It also brings antioxidant protection against the environmental aggressors that contribute to visible aging, and it becomes the moisturizing base for MakeSense® Original Foundation. DayTime Moisturizer – Dry supports skin renewal and moisture retention with stem-cell and peptide care. Multi-weight Hyaluronic Acid supplies all-day hydration, while barrier care helps skin look smoother and plumper. Beauty Book 2026 (p. 12).

In DayTime Moisturizer – Dry, Bis(Tripeptide-1) Copper Acetate supports firmer-looking skin. Its maker built it for that job. The ingredient manufacturer makes Bis(Tripeptide-1) Copper Acetate for firmer-looking skin and wrinkle care and points to several controlled facial studies. Read the DayTime copper-peptide role and the ingredient maker’s copper-peptide source.
Myrothamnus Flabellifolia (Resurrection) Leaf/Stem Extract hydrates, protects, and revitalizes stressed skin in DayTime Moisturizer – Dry. Explore the Resurrection plant ingredient.
DayTime Moisturizer – Dry gently exfoliates for a brighter-looking complexion. Its ingredient list names Lactic Acid/Glycolic Acid Copolymer, a skin-conditioning ingredient. Read the gentle-exfoliation ingredient role.
Squalane, Glycerin and Aloe Barbadensis (Aloe Vera) Leaf Juice round out the moisture. See DayTime Moisturizer – Dry and its complete ingredient list.

What does Evening Moisturizer – Dry do at night?

Evening Moisturizer – Dry supports skin’s natural recovery during sleep, with benefits for texture, even-looking tone, fine-line appearance and a healthy-looking glow. Canarium Indicum (Nangai) Seed Oil, Limnanthes Alba (Meadowfoam) Seed Oil, Carthamus Tinctorius (Safflower) Seed Oil and Butyrospermum Parkii (Shea) Butter make it the richer cream. Evening Moisturizer – Dry supports the skin’s natural overnight repair cycle and helps minimize the appearance of pores. Stem-cell care and lipids smooth, replenish and restore skin overnight. Beauty Book 2026 (p. 12).

Niacinamide helps minimize the appearance of pores, and Calanthe Discolor (Ebine) Extract, from Calanthe discolor orchid stem cells, helps improve the appearance of sagging skin.
Evening Moisturizer – Dry is highly concentrated with additional SenePlex+® for extra protection during sleep. Its SenePlex+® pairs the orchid stem cells with yeast-and-kelp bioferments, Laminaria Digitata (Kelp) Extract and Saccharomyces Cerevisiae (Yeast) Extract. Read the Evening SenePlex+ formula information.
In Evening Moisturizer – Dry, Nicotiana Benthamiana Hexapeptide-40 sh-Polypeptide-76 supports the look of skin texture and radiance. See the Evening texture-and-radiance peptide role. The ingredient maker produces this fusion peptide using Nicotiana benthamiana plant biotechnology. In a 20-woman, placebo-controlled split-face study of a preparation containing 2% of the Nicotiana Benthamiana Hexapeptide-40 sh-Polypeptide-76 material, applied twice daily, the ingredient’s maker reports 16% lower wrinkle count, 11% lower wrinkle volume and 14% lower wrinkle depth across the full group at day 28. Within the separate 85% responder group, wrinkle depth was 19.4% lower on average. See every result the manufacturer measured, from firmness and elasticity to radiance and hydration.
Read the official ingredients and directions carries its full ingredient list alongside directions and benefits.

How do I use the Dry pair?

Morning. After cleansing, Climate Control and your treatments, smooth on DayTime Moisturizer – Dry as the moisturizing step before foundation.
Evening. After cleansing, apply a quarter-size amount of Evening Moisturizer – Dry to the face and neck. Massage it into skin, then press and roll with your fingertips.

If Dry matches your skin, the matching 3 in 1 Cleanser - Dry opens both routines, and EyeCrème goes on after cleansing and before moisturizer. Build the Dry skincare routine to see the full order. Still choosing? Check which SeneGence routine fits dry skin; it also points to Normal-to-Dry when Dry feels too rich. Explore the complete day-to-night beauty system to connect both moisturizers with the rest of your beauty day.

DayTime Moisturizer – Dry · Read the official ingredients and directions.

DayTime Moisturizer – Dry

Choose DayTime Moisturizer – Dry, our lightweight daily moisturizer with SenePlex+®, to replenish and restore moisture, refine texture, even skin tone and diminish the appearance of fine lines and wrinkles for a more youthful look.

SenePlex+®

How to use DayTime Moisturizer – Dry

Nourish your skin directly after washing with the 3 in 1 Cleanser. The DayTime Moisturizers provide moisture and act as the base upon which to apply MakeSense® Original Foundation.

Read the ingredients

Aqua/Water/Eau C12-20 Acid PEG-8 Ester Caprylic/Capric Triglyceride Glycerin Squalane Butylene Glycol Cetearyl Alcohol Propanediol Paeonia Lactiflora (Chinese Peony) Root Extract Caprylic/Capric/Myristic/Stearic Triglyceride Aloe Barbadensis (Aloe Vera) Leaf Juice Hydrolyzed Opuntia Ficus-Indica (Prickly Pear) Flower Extract Calanthe Discolor (Ebine) Extract Aspergillus Ferment Panax Ginseng (Asian Ginseng) Extract Arnica Montana (Arnica) Flower Extract Camellia Sinensis (Green Tea) Leaf Extract Myrothamnus Flabellifolia (Resurrection) Leaf/Stem Extract Sodium Hyaluronate Sodium Hyaluronate Crosspolymer-2 Hydrolyzed Sodium Hyaluronate Sodium Acetylated Hyaluronate Sodium Hyaluronate Crosspolymer Palmitoyl SH-Octapeptide-24 Amide Palmitoyl SH-Tripeptide-5 Norisoleucyl SH-Nonapeptide-1 Bis(Tripeptide-1) Copper Acetate Lactic Acid/Glycolic Acid Copolymer Dimethicone Carbomer Ceteth-10 Phosphate Dicetyl Phosphate Potassium Sorbate Ethylhexylglycerin Allantoin Sodium Hydroxide Trisodium Ethylenediamine Disuccinate Caprylyl Glycol 1 2-Hexanediol Pentylene Glycol Xanthan Gum Gluconolactone Ascorbic Acid Citric Acid Sodium Benzoate Tocopherol Sorbic Acid Polyvinyl Alcohol Calcium Gluconate Copper PCA Magnesium PCA Zinc PCA Phenoxyethanol Parfum/Fragrance Hexyl Cinnamal Linalool Citronellol Eugenol.

How to choose & use Official product page Formula and sources

Evening Moisturizer – Dry

Choose Evening Moisturizer – Dry, our thick, rich night cream concentrated with additional SenePlex+®, to support the skin's natural recovery while you sleep, refine texture, even skin tone and diminish the appearance of fine lines and wrinkles.

SenePlex+®

How to use Evening Moisturizer – Dry

After using SeneGence 3 in 1 Cleanser, apply a quarter size amount to the face and neck daily. Gently massage your moisturizer into the skin. Use your fingertips to press and roll after you’ve massaged it into the skin.

Read the ingredients

Aqua/Water/Eau Carthamus Tinctorius (Safflower) Seed Oil Canarium Indicum (Nangai) Seed Oil Limnanthes Alba (Meadowfoam) Seed Oil Butylene Glycol Pentylene Glycol Butyrospermum Parkii (Shea) Butter Niacinamide Cetearyl Alcohol Paeonia Lactiflora (Chinese Peony) Root Extract Candelilla/Jojoba/Rice Bran Polyglyceryl-3 Esters Glyceryl Stearate Glycerin Behenyl Alcohol Calanthe Discolor (Ebine) Extract Oryza Sativa (Rice) Bran Extract Aspergillus Ferment Panax Ginseng (Asian Ginseng) Extract Hydrolyzed Opuntia Ficus-Indica (Prickly Pear) Flower Extract Helianthus Annuus (Sunflower) Extract Rosmarinus Officinalis (Rosemary) Leaf Extract Arnica Montana (Arnica) Flower Extract Camellia Sinensis (Green Tea) Leaf Extract Aloe Barbadensis (Aloe Vera) Leaf Juice Laminaria Digitata (Kelp) Extract Saccharomyces Cerevisiae (Yeast) Extract Palmitoyl SH-Tripeptide-5 Norisoleucyl SH-Nonapeptide-1 Nicotiana Benthamiana Hexapeptide-40 SH-Polypeptide-76 Palmitoyl SH-Octapeptide-24 Amide Lactic Acid/Glycolic Acid Copolymer Sodium Acetylated Hyaluronate Sodium Hyaluronate Sodium Hyaluronate Crosspolymer-2 Hydrolyzed Sodium Hyaluronate Tocopherol Sodium Stearoyl Lactylate Ethylhexylglycerin Sodium Stearoyl Glutamate Polyacrylate Crosspolymer-6 Xanthan Gum Trisodium Ethylenediamine Disuccinate 1 2-Hexanediol Caprylyl Glycol Gluconolactone T-Butyl Alcohol Sodium Benzoate Panthenol Sorbic Acid Polyvinyl Alcohol Calcium Gluconate Urea* Glucosamine HCl Copper PCA Magnesium PCA Zinc PCA Citric Acid Phenoxyethanol Parfum/Fragrance Hexyl Cinnamal Linalool Citronellol Eugenol. *Synthetic

How to choose & use Official product page Formula and sources

Study results at a glance

Nicotiana fusion peptide — 28-day skin-appearance study10 results

Nicotiana fusion peptide — 28-day skin-appearance study
Result	Kind of result	When it was measured
For Nicotiana Benthamiana Hexapeptide-40 sh-Polypeptide-76, the ingredient manufacturer reports increased expression of selected genes associated with epidermal lipids and barrier function after 24 and 48 hours in primary human keratinocytes exposed to 20 ng/mL active, stated as 2% material.	Ingredient study	24 hours; 48 hours
For Nicotiana Benthamiana Hexapeptide-40 sh-Polypeptide-76, the ingredient manufacturer reports dose-responsive collagen I after 48 hours in adult human dermal fibroblasts and describes its assay-specific potency as four times the retinol reference.	Ingredient study	48 hours
For Nicotiana Benthamiana Hexapeptide-40 sh-Polypeptide-76, the ingredient manufacturer reports qualitative increases in epidermal thickness and lipid staining at day 8 in an exploratory human-skin explant from one 52-year-old donor treated with a cream containing 1.5% material.	Ingredient study	day 8
In a 20-woman, placebo-controlled split-face study of Nicotiana Benthamiana Hexapeptide-40 sh-Polypeptide-76, the ingredient manufacturer used a preparation containing 2% material, applied twice daily. At day 28, it reported 16% lower wrinkle count, 11% lower wrinkle volume and 14% lower wrinkle depth across the full study group. Within the separate 85% responder group, wrinkle depth was 19.4% lower on average.	Measured result	day 28
For Nicotiana Benthamiana Hexapeptide-40 sh-Polypeptide-76, the ingredient manufacturer reports whole-cohort firmness 11% higher and elasticity 6% higher at day 28 in the 20-woman placebo-controlled split-face study using 2% material twice daily; the 95% responder subsets averaged 12.6% and 6.1% higher.	Measured result	day 28

Show 5 more results

Nicotiana fusion peptide — 28-day skin-appearance study, more results
Result	Kind of result	When it was measured
For Nicotiana Benthamiana Hexapeptide-40 sh-Polypeptide-76, the ingredient manufacturer reports whole-cohort pore diameter 11.6% lower at day 28 in the 20-woman placebo-controlled split-face study; the 80% responder subset averaged 16.2% lower, with improvement up to 44%.	Measured result	day 28
For Nicotiana Benthamiana Hexapeptide-40 sh-Polypeptide-76, the ingredient manufacturer reports whole-cohort radiance 12.5% higher at day 28 in the 20-woman placebo-controlled split-face study; the 90% responder subset averaged 14.4% higher, with improvement up to 42%.	Measured result	day 28
For Nicotiana Benthamiana Hexapeptide-40 sh-Polypeptide-76, the ingredient manufacturer reports whole-cohort hydration 12.4% higher and transepidermal water loss 9.5% lower at day 28 in the 20-woman placebo-controlled split-face study; hydration had 100% responders, while the 90% water-loss responder subset averaged 11.2% lower.	Measured result	day 28
For Nicotiana Benthamiana Hexapeptide-40 sh-Polypeptide-76, the ingredient manufacturer reports whole-cohort skin roughness 6.9% lower at day 28 in the 20-woman placebo-controlled split-face study; the 75% responder subset averaged 12.6% lower, with improvement up to 26%.	Measured result	day 28
For Nicotiana Benthamiana Hexapeptide-40 sh-Polypeptide-76, the ingredient manufacturer reports skin thickness 8.0% higher among the 85% responder subset at day 28 in the 20-woman placebo-controlled split-face ultrasound study, with improvement up to 16%.	Measured result	day 28

Who took part: Human study: 20 women ages 45–65 using 2% supplier material twice daily for 28 days
How it was evaluated: Keratinocyte and fibroblast assays, a human skin-explant model, and a 20-woman placebo-controlled split-face study using instrumental wrinkle, firmness, pore, radiance, hydration, and water-loss measures
Statistical context: Across the human study, the ingredient manufacturer reports improvements in wrinkles, firmness, radiance, pores, hydration, and water loss at day 28.

See the full finding: Nicotiana fusion peptide — 28-day skin-appearance study · Open the source document (PDF)

Full ingredient lists

DayTime Moisturizer – DryIngredient guide

Official product reference checked September 18, 2026. View DayTime Moisturizer – Dry on SeneGence

Evening Moisturizer – DryIngredient guide

*Synthetic

Official product reference checked September 18, 2026. View Evening Moisturizer – Dry on SeneGence