Do you put sunscreen on before or after moisturizer?
Quick answer
After. Sunscreen is the last step of your morning skincare, after serums and moisturizer and before primer and foundation. One SeneGence step does both jobs: Microbiome Defense Daytime Moisturizer SPF 15 gives broad-spectrum UVA/UVB protection with Zinc Oxide 6% and Octisalate 5%. See its sunscreen label.
By SeneGence · 
Alan Kante, publisher · Updated
- 2 min read
- SenePlex+®
- Microbiome Collection
Does SeneGence make sunscreen?
Yes. Apply Microbiome Defense Daytime Moisturizer SPF 15 generously and evenly as the last skincare step, 15 minutes before sun exposure, and reapply at least every 2 hours; use a water-resistant sunscreen if swimming or sweating.
What does Microbiome Defense Daytime Moisturizer SPF 15 do for skin?
Microbiome Defense Daytime Moisturizer SPF 15 provides broad-spectrum UVA/UVB protection with Zinc Oxide and Octisalate. Antioxidants defend against blue light and environmental stressors, while probiotic care supports microbiome resilience and clearer-looking skin. Beauty Book 2026 (p. 13). Lactobacillus Ferment gives skin a supple feel and filtered yeast ferment helps the formula hold on to moisture, so the step that protects your skin also brings lightweight morning moisture. Explore the complete daytime formula or its sunscreen label.
Where does SPF go in a SeneGence morning routine?
- Cleanse.
- Prepare and treat: Climate Control, Microbiome Boosting Serum or your other serums.
- Moisturize, if you use a separate DayTime Moisturizer for your skin type.
- Finish skincare with Microbiome Defense Daytime Moisturizer SPF 15.
- Then add MakeSense® Silk Primer & Pore Minimizer and Foundation.
See the full morning order. The Microbiome formulas are made for oily-to-sensitive skin; if you wear a DayTime Moisturizer for another skin type, apply it first and finish with Microbiome Defense. Using a different SPF product? Follow that product’s own directions for timing and reapplication; for swimming or sweating, choose a water-resistant sunscreen. Microbiome Defense Daytime Moisturizer SPF 15.
At night, the collection’s Restorative Evening Moisturizer takes over.
Where it fits
Oily to Sensitive skin routine
- Step 1 Cleanse Microbiome Correcting Cleanser
- Step 2 Morning moisture and labeled sun protection Microbiome Defense Daytime Moisturizer SPF 15
- Step 3 Evening moisture Microbiome Restorative Evening Moisturizer
Skin-type regimens follow the SeneGence Beauty Book 2026, pp. 10–13.
Microbiome Defense Daytime Moisturizer SPF 15
Choose Microbiome Defense Daytime Moisturizer SPF 15 for lightweight, lasting daytime hydration with broad-spectrum SPF 15 sun protection, antioxidants and probiotic care for sensitive to oily skin.
SenePlex+®How to use Microbiome Defense Daytime Moisturizer SPF 15
Apply Microbiome Defense Daytime Moisturizer SPF 15 generously and evenly as the last skincare step, 15 minutes before sun exposure. Reapply at least every 2 hours.
Read the ingredients
Active IngredientsZinc Oxide (6%)Octisalate (5%) Inactive IngredientsAqua/Water/Eau Butylene Glycol Butyloctyl Salicylate Isoamyl Laurate Cetearyl Olivate Caprylic/Capric Glycerides Helianthus Annuus (Sunflower) Seed Wax Lactobacillus Ferment Vegetable Oil Sorbitan Olivate Polyglyceryl-6 Stearate Coco-Caprylate/Caprate Glycerin Saccharomyces Ferment Filtrate Hydroxyacetophenone 1 2-Hexanediol Ammonium Acryloyldimethyltaurate/VP Copolymer Aronia Melanocarpa Fruit Extract Polyglyceryl-6 Polyhydroxystearate Cetyl Alcohol Polyglyceryl-6 Polyricinoleate Polyglyceryl-6 Behenate Simmondsia Chinensis (Jojoba) Seed Oil Lecithin Xanthan Gum Tetrahexyldecyl Ascorbate Tocopherol Ascorbyl Palmitate Bisabolol O-Cymen-5-Ol Sargassum Glaucescens Extract Curcuma Longa (Turmeric) Root Extract Helianthus Annuus (Sunflower) Extract Tocopheryl Acetate Panthenol Calanthe Discolor (Ebine) Extract Aloe Barbadensis (Aloe Vera) Leaf Juice Hydrolyzed Opuntia Ficus-Indica (Prickly Pear) Flower Extract Sodium Hyaluronate Citric Acid Gluconolactone Caprylyl Glycol Sodium Benzoate Calcium Gluconate Laminaria Digitata (Kelp) Extract Saccharomyces Cerevisiae (Yeast) Extract Orchis Mascula (Orchid) Flower Extract Phenoxyethanol Urea* Glucosamine HCl.*Synthetic
Full ingredient list
Microbiome Defense Daytime Moisturizer SPF 15Ingredient guide
Active IngredientsZinc Oxide (6%)Octisalate (5%) Inactive IngredientsAqua/Water/Eau Butylene Glycol Butyloctyl Salicylate Isoamyl Laurate Cetearyl Olivate Caprylic/Capric Glycerides Helianthus Annuus (Sunflower) Seed Wax Lactobacillus Ferment Vegetable Oil Sorbitan Olivate Polyglyceryl-6 Stearate Coco-Caprylate/Caprate Glycerin Saccharomyces Ferment Filtrate Hydroxyacetophenone 1 2-Hexanediol Ammonium Acryloyldimethyltaurate/VP Copolymer Aronia Melanocarpa Fruit Extract Polyglyceryl-6 Polyhydroxystearate Cetyl Alcohol Polyglyceryl-6 Polyricinoleate Polyglyceryl-6 Behenate Simmondsia Chinensis (Jojoba) Seed Oil Lecithin Xanthan Gum Tetrahexyldecyl Ascorbate Tocopherol Ascorbyl Palmitate Bisabolol O-Cymen-5-Ol Sargassum Glaucescens Extract Curcuma Longa (Turmeric) Root Extract Helianthus Annuus (Sunflower) Extract Tocopheryl Acetate Panthenol Calanthe Discolor (Ebine) Extract Aloe Barbadensis (Aloe Vera) Leaf Juice Hydrolyzed Opuntia Ficus-Indica (Prickly Pear) Flower Extract Sodium Hyaluronate Citric Acid Gluconolactone Caprylyl Glycol Sodium Benzoate Calcium Gluconate Laminaria Digitata (Kelp) Extract Saccharomyces Cerevisiae (Yeast) Extract Orchis Mascula (Orchid) Flower Extract Phenoxyethanol Urea* Glucosamine HCl.*Synthetic
Official product reference checked September 18, 2026. View Microbiome Defense Daytime Moisturizer SPF 15 on SeneGence