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Product Basics

The Microbiome Collection: Four Products, Two Dayparts

When your skin's surface ecosystem is balanced, skin looks resilient. Four products protect that state: cleanse comfortably, layer lightweight hydration, finish with broad-spectrum SPF 15 by day, and choose richer softness and barrier comfort at night.

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section 01

Why a Balanced Skin Surface Is Worth Protecting

why it matters

product value & fit

Resilient-looking skin is not luck. Your skin's surface carries an invisible ecosystem of its own, the skin microbiome. When it is balanced, skin looks resilient; when it is disrupted, skin can look reactive, uneven, congested, and tired.

Balance is easy to lose. Harsh surfactants, antibacterial agents, and over-cleansing can strip the surface until skin feels tight rather than clean — and that tight, stripped feeling is disruption talking, not a better cleanse.

The Microbiome Collection was designed with that balance in mind: comfortable cleansing instead of stripping, steady lightweight hydration, and daypart finishes that keep skin looking calm, even, and resilient.

how to use itselection, application & troubleshooting

Open with the state, not the shelf. Ask what a stressed week looks like on the client's skin (reactive, uneven, congested, tired), then name the alternative worth protecting: calm, comfortable, resilient-looking. Introduce the four jobs only after the state matters; every product lands better when it answers a reason the client already owns.

the scienceformula · mechanism · evidence

The skin microbiome is the community of bacteria, fungi, and viruses that naturally lives on the skin's surface and forms part of its protective ecosystem. The acid mantle, a thin and slightly acidic film of sebum and sweat, belongs to the same surface system; after cleansing, a tight, stripped feeling can signal barrier disruption rather than a cleaner finish. That is why this collection begins with mild cleansing and lightweight hydration before either daypart finish.

section 02

Microbiome Collection Order for Morning and Evening

Microbiome Collection Order for Morning and Evening
section 02Microbiome Collection Order for Morning and Evening

why it matters

product value & fit

Choose the Microbiome Collection when skin can feel oily, sensitive, troubled, or stressed and you want balance without making one harsh cleanser or one heavy cream do every job.

The Microbiome Collection contains Microbiome Correcting Cleanser, Microbiome Boosting Serum, Microbiome Defense Daytime Moisturizer SPF 15, and Microbiome Restorative Evening Moisturizer.

Morning and evening share Correcting Cleanser and Boosting Serum. Then the clock changes the finish: Defense Daytime Moisturizer SPF 15 brings lightweight moisture and broad-spectrum protection; Restorative Evening Moisturizer brings richer softness, cushion, and barrier comfort.

Four formulas. Four distinct jobs. One easy morning-and-evening rhythm.

how to use itselection, application & troubleshooting

Show the routines side by side: Cleanser → Boosting Serum → the moisturizer for that daypart. For a fuller SeneGence routine, Climate Control adds plumping hydration after cleansing and before Boosting Serum, while remaining outside the four-product collection. After skincare, Glowify® Microbiome Serum Primer begins makeup prep outside the four-product set.

the scienceformula · mechanism · evidence

The skin microbiome is the community of microorganisms living on the surface. This collection uses ferment-derived ingredients across four formulas, then changes the surrounding architecture by job: a mild cleansing base, a multi-humectant serum, labeled sunscreen actives, and a richer barrier-lipid night cream. See where the collection sits in the complete skincare routine.

section 03

Four Microbiome Formulas, Four Different Jobs

Four Microbiome Formulas, Four Different Jobs
section 03Four Microbiome Formulas, Four Different Jobs

why it matters

product value & fit

Four bottles earn their place only if each solves a different part of the day.

Correcting Cleanser removes impurities and excess oil for a clean, comfortable rinse. Boosting Serum builds lightweight water-binding hydration morning and evening. Defense Daytime Moisturizer adds lightweight moisture, antioxidant care, and labeled broad-spectrum SPF 15. Restorative Evening Moisturizer brings extended moisture, softness, barrier comfort, and help improving the appearance of fine lines.

Ferment-derived ingredients appear across all four formulas, but the full blend is what makes each product feel and work differently: cleansers and supporting ingredients, water-binding humectants, sunscreen actives, or barrier lipids and emollients.

how to use itselection, application & troubleshooting

Lead with the four finished-product jobs: cleanse comfortably, hydrate lightly, protect by day, and cushion by night. Ferment-derived ingredients appear in every formula, but the customer payoff comes from the finished product as a whole. Name the product, the experience it creates, and where it fits in the day.

the scienceformula · mechanism · evidence

The shared fact is presence, not one universal ferment effect. Correcting Cleanser contains Streptococcus Thermophilus Ferment and Lactobacillus/Punica Granatum Fruit Ferment Extract. Boosting Serum contains Lactobacillus Ferment and Sphingomonas Ferment Extract. Defense Daytime Moisturizer SPF 15 contains Lactobacillus Ferment and Saccharomyces Ferment Filtrate. Restorative Evening Moisturizer contains Lactobacillus/Punica Granatum Fruit Ferment Extract and Lactobacillus Ferment. Each formula earns its customer job through a different supporting architecture: the cleanser's mild surfactant blend, the serum's humectant system, the daytime moisturizer's cosmetic base and labeled sunscreen actives, or the evening moisturizer's barrier lipids and emollients. Open the current collection formula map.

section 04

Microbiome Correcting Cleanser: Clean Without a Stripped Finish

Microbiome Correcting Cleanser: Clean Without a Stripped Finish

why it matters

product value & fit

Fresh and clear should not mean tight. Microbiome Correcting Cleanser uses a mild cleansing base to remove impurities and excess oil while keeping a clean, comfortable, hydrated finish as the goal.

Niacinamide, Salicylic Acid, Gluconolactone, Sodium Hyaluronate, and the ferment-derived care layer add the oil-aware, soothing, and radiance story. Judge the product a minute after the towel: comfortable skin is ready for the serum that follows.

how to use itselection, application & troubleshooting

Morning and evening, massage about a dime-size amount over damp face, neck, and décolletage, then rinse thoroughly; repeat the evening cleanse only when needed. Ask what she notices in the first minute afterward. Comfortable and clear sets up the next layers; repeated tightness points toward another cleanser lane.

the scienceformula · mechanism · evidence

Sodium Cocoyl Isethionate, Cocamidopropyl Betaine, and Decyl Glucoside form the mild cleansing base. Streptococcus Thermophilus Ferment and Lactobacillus/Punica Granatum Fruit Ferment Extract carry the ferment-derived layer; Niacinamide, Gluconolactone, Salicylic Acid, Sodium Hyaluronate, and Hamamelis Virginiana Water round out the cleanser’s oil, pore, hydration, and comfort story. Open the current cleanser formula record.

section 05

Apply Microbiome Boosting Serum Before Either Moisturizer

Apply Microbiome Boosting Serum Before Either Moisturizer
section 05Apply Microbiome Boosting Serum Before Either Moisturizer

why it matters

product value & fit

Microbiome Boosting Serum is the collection's lightweight hydration engine, made for every skin type and easy to add to your existing routine. Whether you use Dry, Normal-to-Dry, or Normal-to-Oily skincare, apply it after cleansing and before your daypart moisturizer.

Three forms of hyaluronic acid plus Sodium Polyglutamate create layered water binding without the weight of a rich cream. Lactobacillus Ferment and Sphingomonas Ferment Extract carry the collection's ferment-derived care into this shared AM/PM serum.

Morning or evening, it adds hydration without asking you to rebuild the rest of your routine.

how to use itselection, application & troubleshooting

After cleansing, dispense two to four pumps over face, neck, and décolletage. Massage until absorbed, then continue with treatments and the moisturizer for that daypart. When using the fuller SeneGence sequence, Climate Control goes before this serum. This lightweight serum fits every skin type and can join an existing routine.

the scienceformula · mechanism · evidence

Sodium Hyaluronate, Hyaluronic Acid, and Sodium Hyaluronate Crosspolymer give the serum three water-binding forms; Sodium Polyglutamate adds a separate humectant film. Inositol, Caulerpa Lentillifera Extract, Glycerin, Ficus Carica Fruit Extract, Lactobacillus Ferment, and Sphingomonas Ferment Extract make up the current moisture, botanical, and ferment-derived architecture. Open the current serum formula record.

section 06

Use Microbiome Defense Daytime Moisturizer SPF 15 in the Morning

Use Microbiome Defense Daytime Moisturizer SPF 15 in the Morning

why it matters

product value & fit

Morning skin should not have to choose between comfortable moisture and its sunscreen step. Microbiome Defense Daytime Moisturizer SPF 15 gives the collection a lightweight finish with broad-spectrum protection and antioxidant care; massaged in gently, it disappears with no white cast to work out.

Lactobacillus Ferment and Saccharomyces Ferment Filtrate continue the collection's ferment-derived care; Sodium Hyaluronate draws and binds water. You leave the morning with lightweight moisture, antioxidant care, and labeled broad-spectrum SPF 15 in one formula.

how to use itselection, application & troubleshooting

Once serum and treatments have settled, smooth Microbiome Defense Daytime Moisturizer SPF 15 evenly over the face, neck, and décolletage. Treat it as the labeled sun-protection step and follow the Drug Facts label for amount, timing, and reapplication.

the scienceformula · mechanism · evidence

Microbiome Defense Daytime Moisturizer SPF 15 Drug Facts list Zinc Oxide 6% and Octisalate 5% as active sunscreen ingredients. Lactobacillus Ferment and Saccharomyces Ferment Filtrate carry the ferment-derived layer; Sodium Hyaluronate, Tetrahexyldecyl Ascorbate, Ascorbyl Palmitate, Aronia Melanocarpa Fruit Extract, Sargassum Glaucescens Extract, Curcuma Longa (Turmeric) Root Extract, and Simmondsia Chinensis (Jojoba) Seed Oil supply the moisture and antioxidant cast. Open the current daytime formula record.

section 07

Why the Microbiome Night Moisturizer Uses Ceramide, Cholesterol, and Triglycerides

Why the Microbiome Night Moisturizer Uses Ceramide, Cholesterol, and Triglycerides
section 07Why the Microbiome Night Moisturizer Uses Ceramide, Cholesterol, and Triglycerides

why it matters

product value & fit

Choose Microbiome Restorative Evening Moisturizer when you want more cushion at night: extended moisture, softness, barrier comfort, and help improving the appearance of fine lines.

The richness has a reason. Ceramide NP and Cholesterol bring complementary barrier-lipid roles; Caprylic/Capric Triglyceride and the emollient cast add glide and softness. Fermented pomegranate and Lactobacillus Ferment sit alongside that richer overnight architecture.

The result is a richer nighttime finish purpose-built for softness and cushion.

how to use itselection, application & troubleshooting

At night, repeat Correcting Cleanser and Boosting Serum, then massage about a nickel-size amount of Restorative Evening Moisturizer over face, neck, and décolletage. Press and roll with the fingertips when desired. If the finish repeatedly feels too rich, reduce the amount before moving to another SeneGence moisturizer.

the scienceformula · mechanism · evidence

Ceramide NP and Cholesterol supply complementary barrier-lipid roles. Caprylic/Capric Triglyceride, Squalane, Butyrospermum Parkii (Shea) Butter, Simmondsia Chinensis (Jojoba) Seed Oil, Hydrogenated Olive Oil Unsaponifiables, and Phytosphingosine add emollient comfort. Sodium Hyaluronate adds water binding. Lactobacillus/Punica Granatum Fruit Ferment Extract and Lactobacillus Ferment are the formula's ferment-derived ingredients. Open the current night formula record.

section 08

Who Should Choose the Complete Microbiome Collection?

Who Should Choose the Complete Microbiome Collection?

why it matters

product value & fit

Choose the complete set when sensitive-to-oily, troubled, or stressed-feeling skin wants one coordinated morning-and-evening routine: a comfortable cleanse, a shared hydration step, SPF 15 by day, and richer comfort at night.

Start with Microbiome Boosting Serum when your current cleanser and moisturizers already fit, but you want the collection's lightweight hydration engine in both routines.

how to use itselection, application & troubleshooting

Check three moments: one minute after cleansing, late afternoon, and the next morning. If skin stays comfortable at all three, the set is a good fit. Repeated cleanser tightness, excessive evening richness, or better comfort with another SeneGence skin-type set means this may not be the right set. Change one variable at a time, then compare the same checkpoint. Review the collection answer.

the scienceformula · mechanism · evidence

The set and the serum answer different purchase questions. The set supplies a coordinated cleanser, shared serum, and two daypart finishes. The serum is the lower-commitment entry because it is the only collection member that fits every skin type and can join an existing routine. Shop the complete set or start with Boosting Serum.

Shop the Microbiome SkinCare Regimen Set ↗
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