What is SeneGence's best-selling product?Read
Read the short answer
Color & define · Lips
LipSense® Long-Lasting Liquid Lip Color is SeneGence’s award-winning Global Best Seller.
The SeneGence Review
Get a straight answer about choosing products, building routines, applying LipSense, understanding ingredients and results, or getting to know SeneGence.
Color & define · Lips
LipSense® Long-Lasting Liquid Lip Color is SeneGence’s award-winning Global Best Seller.
Color & define · Lips
Yes. LipSense® lip color is safe for everyday use as directed, and SeneGence tests its products for safety, quality and performance before they reach you.
Lips
SeneGence LipSense® Color is built from a quick-drying Alcohol Denat. carrier, a flexible long-wear film, shade pigments and soothing botanicals, and Moisturizing Gloss seals it with Shea Butter, vitamin E and Glycerin.
Cleanse & remove · Lips
To remove long-wear SeneGence makeup, match the remover to the zone: Fooops!® Dual Phase Color Remover for face and eye color, including ShadowSense® Eyeshadow and waterproof LashSense® mascara; Ooops!™ Lip Color Remover for LipSense®; and Melt-Away Deep Cleansing Balm to melt off a full face as your first cleanse.
Lips
The Permeable Polymer Matrix is the breathable, flexible color film in SeneGence’s LipSense® Long-Lasting Liquid Lip Color: three thin layers set into one film, and because the film is permeable, the conditioners in LipSense® Moisturizing Gloss pass through it to the lips beneath.
Color & define · Lips
LipSense® Long-Lasting Liquid Lip Color is SeneGence’s long-lasting liquid lipstick. Compared with conventional one-tube liquid lipsticks, it uses a three-piece system: three thin layers of Liquid Lip Color, LipSense Moisturizing Gloss on top, and Ooops!™ Lip Color Remover to take it off.
Lips
A brief tingle or mild burning feeling when you apply SeneGence LipSense® Long-Lasting Liquid Lip Color comes from its fast-drying alcohol base evaporating as the color film sets, and dry or unconditioned lips feel it more.
Lips · Brand-affiliated Reddit discussion
It doesn’t have to. SeneGence LipSense® pairs long-wear color with conditioning: three thin layers of Liquid Lip Color set into a breathable film, and LipSense Moisturizing Gloss on top conditions the lips beneath.
Color & define · Lips
Choose SeneGence LipSense® Long-Lasting Liquid Lip Color for extended, customizable wear from three thin layers sealed with Moisturizing Gloss, or LipSense® Cream (formerly HydraMatte) when one-step, Gloss-free color leads.
Color & define · Lips
SeneGence LipSense Long-Lasting Liquid Lip Color offers waterproof, kiss-proof, transfer-proof wear for up to 18 hours.
Color & define · Lips
Apply LipSense® Long-Lasting Liquid Lip Color, SeneGence's long-lasting liquid lipstick, in three thin layers on clean, dry lips, letting each set, then seal with LipSense® Moisturizing Gloss.
Cleanse & remove · Lips
To remove SeneGence LipSense®, dip the Ooops!™ Lip Color Remover wand, gently rub the applicator over the color, and wipe clean with tissue.
Color & define · Lips
SeneGence LipSense® usually looks patchy or flakes when balm or oil is left on the lips, layers go on too thickly, or strokes go back and forth; take it off with Ooops!™ Lip Color Remover and rebuild in thin layers.
Finish · Lips
Start with a sheer neutral SeneGence LipSense® Moisturizing Gloss, Glossy, Pearl or Satin Matte, so your LipSense® shade reads true, then add lightly tinted, richly tinted or glitter Glosses to transform the look without buying a new color.
Finish · Lips
Yes, within the SeneGence line. Seal LipSense® Color with LipSense® Moisturizing Gloss once the third layer has set, and Glowify® Juicy Plumping Lip Gloss is also directed for wear over LipSense®; glosses made outside the LipSense system can soften the color film.
Lips
Choose SeneGence Glowify® Sheer Silk Lip Oil for cushiony hydration and soft blur on bare lips, or Glowify® Juicy Plumping Lip Gloss for a cooling feel and visibly fuller-looking lips, worn bare or over LipSense®.
Color & define · Lips
Choose the SeneGence LipSense® Long-Lasting Lip Liner Pencil, which replaced the earlier liquid liner.
Lips
Choose SeneGence LipSense® Moisturizing Lip Balm to hydrate and comfort bare lips with a matte finish, Lip Line Corrector for smoother-looking lines around the mouth, or Overnight Lip Mask for softer, fuller-looking lips by morning.
Color & define · Lips
LipSense® is SeneGence’s flagship long-lasting liquid lipstick, a wax-free color that sets on your lips as a flexible, breathable film and holds until you take it off.
Target & care · Lips
SeneGence Lip Line Corrector is a targeted treatment for the delicate lip contour, pairing encapsulated peptide complexes with SenePlex+® stem cell technology to visibly smooth vertical lip lines and enhance lip definition.
Lips
Yes. SeneGence spends where you can feel it, on long-wear color, on skincare tested in independent studies, and on the formula instead of a box you would throw away.
Lips
Joni Rogers-Kante is the Founder, CEO and Chairwoman of SeneGence, the high-performance skincare and cosmetics company she started in 1999 as a single mother with no investment capital and one idea: kiss-proof lip color.
Lips
SeneGence was founded in 1999 and marks 27 years in business in 2026.