The SeneGence Review
Get a straight answer about choosing products, building routines, applying LipSense, understanding ingredients and results, or getting to know SeneGence.
Skincare & eye care
Choose SeneGence SeneSerum-C® Hydrating C-Pearls® Serum, with Tetrahexyldecyl Ascorbate, Ergothioneine and Sodium Hyaluronate (a form of hyaluronic acid), for hydrating vitamin C care and an everyday glow; choose C-Bright Dark Spot Corrector, with 3-O-Ethyl Ascorbic Acid, Ferulic Acid and Acetyl Tetrapeptide-2, when dark spots, discoloration and uneven-looking tone lead your decision.
Target & care · Skincare & eye care
Retinol helps skin look brighter and firmer, with less noticeable fine lines over time, and SeneGence Advanced SenePlex+® Renewal Serum with Retinol pairs Retinol and Retinyl Palmitate with Palmitoyl Tripeptide-1 and Palmitoyl Tetrapeptide-7.
Skincare & eye care
Yes. Use SeneGence SeneSerum-C® Hydrating C-Pearls® Serum in the morning and Advanced SenePlex+® Renewal Serum with Retinol at night under Evening Moisturizer, starting every other night and building to nightly use as tolerated.
Skincare & eye care
The skin barrier is your skin’s outermost protective layer, and its lipids help keep water from escaping, which is why a depleted barrier can leave skin feeling tight or uncomfortable. In SeneGence skincare, Microbiome Boosting Serum helps strengthen the skin’s natural barrier, and Microbiome Restorative Evening Moisturizer brings Ceramide NP and Cholesterol for moisture-barrier support.
Skincare & eye care
SenePlex+® is SeneGence’s foundational proprietary anti-aging complex, at work in most of our products. Our extremophile technology is made with extracts and cells that survive in extreme environments. In SenePlex+®, Calanthe discolor orchid stem cells and Orchis Mascula orchid join biofermented yeast and kelp, prickly pear, hyaluronic acid, glucosamine, urea and vitamins B5 and E. SenePlex+® is clinically proven to accelerate skin cell renewal for smoother, brighter, younger-looking skin, and it promotes collagen and protects against everyday stressors.
Skincare & eye care
Skin longevity in skincare means caring for how skin looks and feels over time as its needs change: hydrated, smooth, firm, resilient, even-looking and radiant.
Skincare & eye care
Yes. In SeneGence skincare, plant-derived exosomes work inside GLP Complex™ with SenePlex+® and Exosomes, which carries Centella Asiatica Leaf Vesicles. Its finished-serum study measured improvements in deep-wrinkle and facial-volume appearance.
Skincare & eye care
Yes, when the peptide and the finished formula match the result you want.
Skincare & eye care
Peptides are short chains of amino acids that act as messengers in skincare, each chosen for a specific visible job, such as softer-looking lines or smoother, firmer-looking skin.
Skincare & eye care
Extremophile skincare draws on life that thrives where conditions should destroy it, and for SeneGence the search began in the summer of 2000 at the caldera of the Volcano, Mt. Yasur, on Tanna in Vanuatu.
Skincare & eye care
A resurrection plant can dry out almost completely, then revive when water returns. SeneGence DayTime Moisturizer – Dry carries one, Myrothamnus Flabellifolia (Resurrection) Leaf/Stem Extract, to hydrate, protect and revitalize stressed skin.
Skincare & eye care
Fine volcanic-ash particles help SeneGence Facial Resurfacer polish away dull surface buildup as you massage and rinse, leaving skin smoother and fresher-looking.
Skincare & eye care
Some SeneGence skincare shows results from the first use, and the rest builds over weeks.
Skincare & eye care
“Independently tested” means an outside laboratory evaluated a defined product, ingredient or regimen using a stated method, timeline and visible endpoint.
Skincare & eye care
SeneGence brings copper to firmer-looking skin two ways: Bis(Tripeptide-1) Copper Acetate, the copper peptide in all three DayTime Moisturizers, and Copper Lysinate/Prolinate, a copper complex paired with Methylglucoside Phosphate in NeoTight® Rejuvenating Anti-Wrinkle Serum.
Skincare & eye care
SeneGence puts peptides where each beauty goal lives: Caprooyl Tetrapeptide-3 in GLP Complex™ and SeneCell™ for smoother-looking lines, a tone-care peptide pair in every DayTime and Evening Moisturizer, Palmitoyl Tetrapeptide-50 with Heptapeptide-15 Palmitate in Lip Line Corrector, and Acetyl Tetrapeptide-3 with clover for fuller-looking brows, lashes and hair. Lip Line Corrector visibly improves the appearance of vertical lip lines by up to 30% after six weeks of twice-daily use in an independent clinical study of 35 women ages 40–70, measured by expert grading against baseline. In an independent study of 31 participants measured by image analysis, GLP Complex™ with SenePlex+® and Exosomes reduced the appearance of deep wrinkles by 11.2% at four weeks and 23.4% at eight weeks, and improved the look of facial volume by 8.4% at eight weeks.
Skincare & eye care
Plant exosomes are a kind of vesicle: tiny membrane-bound particles that plant cells release. A secretome is the wider set of everything a cell releases. In SeneGence skincare, plant exosomes appear as Centella Asiatica Leaf Vesicles in GLP Complex™ with SenePlex+® and Exosomes, beside Ornithine HCl, Phospholipids, Glycolipids and Caprooyl Tetrapeptide-3.
Skincare & eye care
In the summer of 2000, SeneGence founder Joni Rogers-Kante took scientists and botanists to Mount Yasur, the active volcano on Vanuatu’s Tanna Island, and came back with three discoveries: an ash that clears, an orchid that inspired SenePlex+® renewal and a seed oil that protects.
Target & care · Skincare & eye care
For the look of facial volume after weight loss, SeneGence makes GLP Complex™ with SenePlex+® and Exosomes, a clinically proven serum that visibly restores lost facial volume, smooths deep wrinkles and firms skin affected by aging, weight loss and lifestyle changes.
Skincare & eye care
By week six of an independent study, every participant agreed that SeneGence NeoTight™ Eye Serum nourished the delicate skin around the eyes, and expert grading measured an improved look of dark circles and puffiness.
Skincare & eye care
Choose by what your eye area needs most: SeneGence NeoTight™ Eye Serum for the look of dark circles and under-eye bags, EyeCrème for richer daily moisture and crow’s feet, and EyeLuminator™ Under Eye Brightening Cream for sheer brightness with your makeup.
Skincare & eye care
Layer SeneGence NeoTight™ Eye Serum first and EyeCrème second, both before your moisturizer; tap EyeLuminator™ on in the morning after skincare, then add Corrective Color Concealer only where you want more coverage.
Skincare & eye care
Apply SeneGence skincare in this order: cleanse, then Climate Control®, then treatments from lightest to richest (for the Triple Cell Renewal Trio, GLP Complex™ with SenePlex+® and Exosomes, then SeneCell™ SenePlex+® StemCell Concentrate), then NeoTight™ Eye Serum and EyeCrème, then Nangai Oil when skin feels dry, and finish with the moisturizer for that time of day.
Skincare & eye care
Serum goes on before moisturizer. In the SeneGence order, cleanse, then use Climate Control®, GLP Complex™, SeneCell™, Nangai Oil when skin feels dry, and the moisturizer for your skin type and time of day.
